Bloody-butcher
Pulmonaria officinalis
Pulmonaria officinalis, commonly known as lungwort, is a traditional plant associated with European herbal medicine. Traditionally, it has not been extensively used in any specific medical practices or traditions. Scientific evidence suggests that 70% ethanolic extracts of Pulmonaria officinalis exhibit antioxidant properties and have dual dose-dependent genotoxic/antigenotoxic effects, indicating potential benefits for mitigating oxidative stress. Genome analysis reveals differences between Pulmonaria obscura and P. officinalis, which may influence their karyotype dynamics. In vitro studies show that the plant extract can activate GLUT4 translocation, suggesting possible antidiabetic properties. No major safety concerns or recorded drug interactions have been identified for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- A 70% ethanolic extract of Pulmonaria officinalis showed antioxidant activity and a dual dose-dependent genotoxic/antigenotoxic effect.
- Genome size, repeatome analysis, and comparative karyotyping provided insights into the genome dynamics and karyotype structure differences within the Pulmonaria officinalis group.
- The study found that extracts from both Pulmonaria obscura and Pulmonaria officinalis partially mitigated peroxynitrite-induced oxidative stress in blood plasma.
- Pulmonaria helvetica shows evidence of hybrid origin through balanced admixture between Pulmonaria officinalis and Pulmonaria mollis s.l., suggesting hybrid speciation.
- Pulmonaria officinalis showed potential as an antidiabetic nutraceutical based on its ability to activate GLUT4 translocation.
Frequently asked questions
What is Bloody-butcher?
Bloody-butcher (Pulmonaria officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bloody-butcher?
5 sourced findings are recorded for Bloody-butcher; the strongest carries evidence grade D. For example: A 70% ethanolic extract of Pulmonaria officinalis showed antioxidant activity and a dual dose-dependent genotoxic/antigenotoxic effect.
How strong is the evidence for Bloody-butcher?
The strongest finding for Bloody-butcher carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bloody-butcher safe? What are the side effects?
No major safety issues are recorded for Bloody-butcher in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bloody-butcher interact with medications?
No drug interactions are recorded for Bloody-butcher in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bloody-butcher?
Bloody-butcher is also known as: Медуница лекарственная, Pulmonaire officinale.
Is Bloody-butcher a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Recent hybrid speciation at the origin of the narrow endemic Pulmonaria helvetica. literature abstract metadata
- T2 Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. literature abstract metadata
- T2 Insulin-Mimetic Activity of Herbal Extracts Identified with Large-Scale Total Internal Reflection Fluorescence Microscopy. literature abstract metadata
- T2 First insight into the genomes of the Pulmonaria officinalis group (Boraginaceae) provided by repeatome analysis and comparative karyotyping. literature abstract metadata
- T2 Assessment of Antioxidant Activity and Dose-Dependent Effect on Genotoxicity/Antigenotoxicity of Pulmonaria officinalis Ethanolic Extract. literature abstract metadata