Pyrola rotundifolia

Pyrola rotundifolia, commonly known as round-leaved wintergreen or small pyrola, is a plant native to North America and found in various habitats such as dunes and forests. Traditionally, no specific uses for this plant have been recorded. Scientifically, the leaves of Pyrola rotundifolia contain high levels of phenols and flavonoids with moderate antioxidant and cytotoxic activity, though these findings are not extensive enough to draw definitive conclusions about its potential medicinal applications. A study also found that an injection combining Pyrola rotundifolia and Astragalus membranaceus showed protective effects on guinea pig cochlea and kidney against gentamicin ototoxicity, indicating some potential for ear and kidney protection. Additionally, research has identified the complete chloroplast genome of Pyrola decorata, confirming its phylogenetic placement within Group I, and noted that Pyrola rotundifolia populations associate with different mycorrhizal communities, with native seeds showing higher germination success than immigrant seeds. Safety-wise, no major issues have been recorded for this plant, and there are currently no reported drug interactions.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.