Reynoutria multiflora
Reynoutria multiflora
Reynoutria multiflora, also known as polygonum multiflorum or Japanese knotweed, is a plant traditionally used in East Asian medicine. While its specific traditional uses are not well-documented, it has been employed for various health conditions. Scientific evidence suggests that the combined use of Reynoutria multiflora and Cullen corylifolium might exacerbate immune-mediated liver injury compared to using either herb alone. Additionally, studies indicate that PM (polymerized monomeric proanthocyanidins) and polygalacic acid from this plant can suppress prostate cancer growth by targeting CDC25B, leading to G2/M-phase cell-cycle arrest. Metabolomic analysis has identified 259 gallic acid-based and 112 catechin-based metabolites in processed Reynoutria multiflora, showing changes in their levels. To date, no significant safety concerns or drug interactions have been reported for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The combined treatment with Reynoutria multiflora and Cullen corylifolium may exacerbate immune-mediated liver injury compared to treatment with either herb alone.
- PM and polygalacic acid from it suppress prostate cancer growth by targeting CDC25B, inducing G2/M-phase cell-cycle arrest.
- Cholesterol sulfate was identified as a potential biomarker for Polygonum multiflorum-induced liver injury based on multi-omics analysis.
- The study identified 259 gallic acid-based and 112 catechin-based metabolites in processed Reynoutria multiflora, showing changes in their levels.
Frequently asked questions
What is Reynoutria multiflora?
Reynoutria multiflora (Reynoutria multiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Reynoutria multiflora?
4 sourced findings are recorded for Reynoutria multiflora; the strongest carries evidence grade D. For example: The combined treatment with Reynoutria multiflora and Cullen corylifolium may exacerbate immune-mediated liver injury compared to treatment with either herb alone.
How strong is the evidence for Reynoutria multiflora?
The strongest finding for Reynoutria multiflora carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Reynoutria multiflora safe? What are the side effects?
No major safety issues are recorded for Reynoutria multiflora in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Reynoutria multiflora interact with medications?
No drug interactions are recorded for Reynoutria multiflora in our sources. This does not rule them out — check with a pharmacist.
Is Reynoutria multiflora a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Processing of Reynoutria multiflora: transformation of catechin and gallic acid derivatives and their identification. literature abstract metadata
- T2 Reynoutria multiflora (Thunb.) Moldenke and its ingredient suppress lethal prostate cancer growth by inducing CDC25B-CDK1 mediated cell cycle arrest. literature abstract metadata
- T2 A new incompatible combination: Reynoutria multiflora combined with Cullen corylifolium enhances idiosyncratic hepatotoxicity under immunological stress. literature abstract metadata
- T2 Identification of potential biomarkers for Polygonum multiflorum-induced liver injury in a clinical cohort: integrating machine learning of metabolomics with transcriptomic profiling. literature abstract metadata