Madders
Rubia
Rubia is a plant traditionally associated with dyeing and textile industries, particularly for producing red colors. While its traditional medicinal uses are not well-documented, it has been explored in various scientific studies. Research indicates that Rubia can be part of a synergistic approach to enhance salt tolerance in plants like Rubia tinctorum and improve wool dyeing processes through color fastness and UV protection. Additionally, self-assembled nanoparticles derived from carbonized Rubia cordifolia have shown promise in modulating the IL-17A/IL-22-C/EBPβ-STAT3 axis to alleviate ulcerative colitis and exhibit anti-cancer properties by inhibiting breast cancer cell viability, migration, and promoting apoptosis. In vitro and in vivo studies suggest potential benefits but require further investigation. No major safety issues or recorded drug interactions have been noted thus far.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that a synergistic application of Ascophyllum nodosum, Salix aegyptiaca, and gum arabic improved salt tolerance in Rubia tinctorum.
- This study optimised a single-bath ultrasound-assisted wool dyeing process using Rubia and Reseda extracts, showing good colour fastness and UV protection.
- This review highlights diverse pharmacological activities from Rubia plants but questions their clinical interchangeability due to varying phytochemical compositions.
- RY significantly inhibited breast cancer cell viability and promoted apoptosis in vitro and reduced tumor growth in vivo.
- Self-assembled nanoparticles from carbonized Rubia cordifolia showed enhanced stability and alleviated ulcerative colitis by modulating the IL-17A/IL-22-C/EBPβ-STAT3 axis.
Frequently asked questions
What is Madders?
Madders (Rubia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Madders?
5 sourced findings are recorded for Madders; the strongest carries evidence grade D. For example: The study found that a synergistic application of Ascophyllum nodosum, Salix aegyptiaca, and gum arabic improved salt tolerance in Rubia tinctorum.
How strong is the evidence for Madders?
The strongest finding for Madders carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Madders safe? What are the side effects?
No major safety issues are recorded for Madders in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Madders interact with medications?
No drug interactions are recorded for Madders in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Madders?
Madders is also known as: Марена, Garance.
Is Madders a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Synergistic ultrasonic dyeing of wool: optimisation of a single-bath process with Rubia and Reseda extracts for eco-friendly textiles. literature abstract metadata
- T2 Synergistic application of Ascophyllum nodosum, Salix aegyptiaca, and gum arabic improves salt tolerance in Rubia tinctorum. literature abstract metadata
- T2 A comprehensive review of Rubia medicinal plants: Traditional uses, botany, phytochemistry, and pharmacological activities. literature abstract metadata
- T2 Exploration of the multi-component, multi-target, and multi-pathway mechanism of Rubia yunnanensis in inhibiting breast cancer based on network pharmacology, molecular docking, and experimental validation. literature abstract metadata
- T2 Discovery of self-assembled nanoparticles from Rubia cordifolia L. before and after carbonization and mechanistic study on their targeted therapy for ulcerative colitis. literature abstract metadata