FolkKB

Santol

Sandoricum koetjape

Sandoricum koetjape is a tropical tree species utilized within various traditional medicine systems. It is traditionally employed as an astringent, carminative, and stomachic, with applications for treating diarrhea, dysentery, ringworm, and spasms. Scientific evidence suggests potential antibacterial activity from certain compounds, though these effects appear modest. Research also indicates that KKA may exhibit anti-colon cancer activity in vitro and in vivo, while new leaf compounds show potential alpha-glucosidase inhibitory activity. No major safety issues or notable drug interactions have been recorded in the available data.

At a glance
Traditionally for
astringent · carminative
Traditions
traditional
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • Compound 7 showed potential antibacterial activity against tested bacteria, though effects were modest. D PMID
  • KKA showed in vitro and in vivo anti-colon cancer activity by regulating various proteins and pathways. D PMID
  • The study identified 7745 transcripts from Kecapi seedlings treated with different LED spectra, providing a dataset for plant growth analysis. D PMID
  • The study identified two new compounds from Sandoricum koetjape leaves that showed potential α-glucosidase inhibitory activity. D PMID

Frequently asked questions

What is Santol?

Santol (Sandoricum koetjape) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Santol traditionally used for?

Traditional sources record Santol for: astringent, carminative, diarrhea, dysentery, ringworm, spasms. This reflects traditional use, not a proven medical treatment.

Which traditions use Santol?

Santol appears in these traditions in our sources: traditional.

What does the scientific evidence say about Santol?

4 sourced findings are recorded for Santol; the strongest carries evidence grade D. For example: Compound 7 showed potential antibacterial activity against tested bacteria, though effects were modest.

How strong is the evidence for Santol?

The strongest finding for Santol carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Santol safe? What are the side effects?

No major safety issues are recorded for Santol in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Santol interact with medications?

No drug interactions are recorded for Santol in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Santol?

Santol is also known as: Сантол.

Is Santol a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Cycloartane-type triterpenoids from the leaves of Sandoricum koetjape and their efficacy on α-glucosidase inhibition activity. literature abstract metadata
  3. T2 Evaluation of in vitro and in vivo anticancer activities of potassium koetjapate: a solubility improved formulation of koetjapic acid against human colon cancer. literature abstract metadata
  4. T2 Transcriptome dataset of leaves treated with different spectra of light-emitting diodes on Sandoricum koetjape Merr. seedlings using cDNA-PCR sequencing with Oxford nanopore technologies. literature abstract metadata
  5. T2 A New Ursane-Type Pentacyclic Triterpenoid from the Tree Bark of Sandoricum koetjape: Antibacterial, DFT, and Molecular Docking Study. literature abstract metadata