Greater Mexican-stonecrop

Sedum dendroideum

Sedum dendroideum is a plant traditionally used with limited documentation. Scientific evidence suggests potential benefits for conditions such as corneal lesions, gastric ulcers, and pterygium, showing immunomodulatory effects and promoting tissue healing. For corneal lesions, it has been observed to reduce TNF-α and IL-1α while maintaining IL-10 expression. In gastric ulcer treatment, SDI (Sedum dendroideum) accelerated healing by enhancing epithelial cell proliferation, reducing inflammation, and restoring antioxidant activities. It also demonstrated anti-fibrotic properties in pterygium fibroblasts, with potential for use in burn injuries through enhanced fibroblast activity, collagen fiber formation, and blood vessel growth. No significant safety concerns or drug interactions have been reported to date.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The treatment with a dichloromethane extract of Sedum dendroideum showed an immunomodulatory effect, reducing TNF-α and IL-1α while maintaining IL-10 expression in corneal lesions. D PMID
  • SDI accelerated gastric ulcer healing in rats by promoting epithelial cell proliferation, reducing inflammation, and restoring antioxidant activities. D PMID
  • Sedum dendroideum decreased the viability and gene expression of pterygium fibroblasts in a dose-dependent manner. D PMID
  • The electrospinning PLA membrane, alone or with Sedum dendroideum extract, promoted healing by increasing fibroblasts, collagen fibers, and blood vessels in burn injuries. D PMID

Frequently asked questions

What is Greater Mexican-stonecrop?

Greater Mexican-stonecrop (Sedum dendroideum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Greater Mexican-stonecrop?

4 sourced findings are recorded for Greater Mexican-stonecrop; the strongest carries evidence grade D. For example: The treatment with a dichloromethane extract of Sedum dendroideum showed an immunomodulatory effect, reducing TNF-α and IL-1α while maintaining IL-10 expression in corneal lesions.

How strong is the evidence for Greater Mexican-stonecrop?

The strongest finding for Greater Mexican-stonecrop carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Greater Mexican-stonecrop safe? What are the side effects?

No major safety issues are recorded for Greater Mexican-stonecrop in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Greater Mexican-stonecrop interact with medications?

No drug interactions are recorded for Greater Mexican-stonecrop in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Greater Mexican-stonecrop?

Greater Mexican-stonecrop is also known as: Orpin très élevé, Orpin à allure d'arbre.

Is Greater Mexican-stonecrop a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats. literature abstract metadata
  2. T2 Effectiveness of the polyphenols-rich Sedum dendroideum infusion on gastric ulcer healing in rats: Roles of protective endogenous factors and antioxidant and anti-inflammatory mechanisms. literature abstract metadata
  3. T2 Corneal Healing and Recovery of Ocular Crystallinity with a Dichloromethane Extract of Sedum dendroideum D.C. in a Novel Murine Model of Ocular Pterygium. literature abstract metadata
  4. T2 Phytochemical Profile and Antioxidant and Antiproliferative Activity of Sedum dendroideum on Pterygium Fibroblasts. literature abstract metadata