Greater Mexican-stonecrop
Sedum dendroideum
Sedum dendroideum, also known as tree stonecrop, is a plant traditionally used in some herbal practices but lacks specific documented uses. Scientific studies have shown potential immunomodulatory effects with its dichloromethane extract, reducing inflammatory markers such as TNF-α and IL-1α while maintaining IL-10 expression in corneal lesions. Additionally, it has demonstrated efficacy in accelerating gastric ulcer healing in rats by promoting epithelial cell proliferation, reducing inflammation, and restoring antioxidant activities. In burn injuries, the electrospinning PLA membrane containing Sedum dendroideum extract promoted healing through increased fibroblasts, collagen fibers, and blood vessel formation. The plant also showed promise in decreasing the viability and expression of VEGF and CTGF in pterygium fibroblasts in a dose-dependent manner. No significant safety concerns or recorded drug interactions have been noted for Sedum dendroideum to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The treatment with a dichloromethane extract of Sedum dendroideum showed an immunomodulatory effect, reducing TNF-α and IL-1α while maintaining IL-10 expression in corneal lesions.
- SDI accelerated gastric ulcer healing in rats by promoting epithelial cell proliferation, reducing inflammation, and restoring antioxidant activities.
- Sedum dendroideum decreased the viability and gene expression of pterygium fibroblasts in a dose-dependent manner.
- The electrospinning PLA membrane, alone or with Sedum dendroideum extract, promoted healing by increasing fibroblasts, collagen fibers, and blood vessels in burn injuries.
Frequently asked questions
What is Greater Mexican-stonecrop?
Greater Mexican-stonecrop (Sedum dendroideum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Greater Mexican-stonecrop?
4 sourced findings are recorded for Greater Mexican-stonecrop; the strongest carries evidence grade D. For example: The treatment with a dichloromethane extract of Sedum dendroideum showed an immunomodulatory effect, reducing TNF-α and IL-1α while maintaining IL-10 expression in corneal lesions.
How strong is the evidence for Greater Mexican-stonecrop?
The strongest finding for Greater Mexican-stonecrop carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Greater Mexican-stonecrop safe? What are the side effects?
No major safety issues are recorded for Greater Mexican-stonecrop in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Greater Mexican-stonecrop interact with medications?
No drug interactions are recorded for Greater Mexican-stonecrop in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Greater Mexican-stonecrop?
Greater Mexican-stonecrop is also known as: Orpin très élevé, Orpin à allure d'arbre.
Is Greater Mexican-stonecrop a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats. literature abstract metadata
- T2 Effectiveness of the polyphenols-rich Sedum dendroideum infusion on gastric ulcer healing in rats: Roles of protective endogenous factors and antioxidant and anti-inflammatory mechanisms. literature abstract metadata
- T2 Corneal Healing and Recovery of Ocular Crystallinity with a Dichloromethane Extract of Sedum dendroideum D.C. in a Novel Murine Model of Ocular Pterygium. literature abstract metadata
- T2 Phytochemical Profile and Antioxidant and Antiproliferative Activity of Sedum dendroideum on Pterygium Fibroblasts. literature abstract metadata