Little club-moss
Selaginella tamariscina
Selaginella tamariscina, commonly known as spikemoss, is a plant traditionally used in East Asian medicine. While its specific uses are not well-documented, studies have shown that extracts from this plant may reduce UVA-induced skin photodamage by modulating apoptosis and autophagy. Additionally, robustaflavone has been observed to promote osteogenic differentiation and bone regeneration in dental pulp stem cells without affecting BMP2-Smad signaling pathways. Amentoflavone from Selaginella tamariscina has also demonstrated the ability to reduce UVB-induced skin damage by modulating PAR2-driven signaling pathways, as well as decreasing oxidative stress, inflammation, and apoptosis both in vitro and in vivo. To date, no major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Selaginella tamariscina extract reduces UVA-induced skin photodamage by modulating apoptosis and autophagy.
- Robustaflavone promoted osteogenic differentiation and bone regeneration in dental pulp stem cells by enhancing early migration and late-stage mineralization without affecting BMP2-Smad signaling.
- Amentoflavone from Selaginella tamariscina reduced UVB-induced skin damage by modulating PAR2-driven signaling pathways.
- STE and amentoflavone reduce UVB-induced skin aging by activating AMPK.
Frequently asked questions
What is Little club-moss?
Little club-moss (Selaginella tamariscina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Little club-moss?
4 sourced findings are recorded for Little club-moss; the strongest carries evidence grade D. For example: Selaginella tamariscina extract reduces UVA-induced skin photodamage by modulating apoptosis and autophagy.
How strong is the evidence for Little club-moss?
The strongest finding for Little club-moss carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Little club-moss safe? What are the side effects?
No major safety issues are recorded for Little club-moss in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Little club-moss interact with medications?
No drug interactions are recorded for Little club-moss in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Little club-moss?
Little club-moss is also known as: Плаунок тамарисковый.
Is Little club-moss a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Selaginella Tamariscina extract reduces UVA-induced skin photodamage via regulating apoptosis and autophagy by AKT phosphorylation. literature abstract metadata
- T2 Amentoflavone mitigates UVB-induced epidermal photoaging by antagonizing PAR2-driven PI3K/Akt/FoxO6 oxidative-stress signaling. literature abstract metadata
- T2 Selaginella tamariscina extract and amentoflavone ameliorate UVB-induced skin aging via AMPK activation. literature abstract metadata
- T2 Robustaflavone promotes osteogenic potential and bone regeneration of dental pulp stem cells by modulating mitochondrial activity and smad-independent signaling. literature abstract metadata