Siphonodon celastrineus
Siphonodon celastrineus
Siphonodon celastrineus is a plant native to certain regions of Asia and has not been extensively used in traditional medicine. Scientific studies have shown promising results, with high cytotoxic activity observed against some cancer cell lines in vitro from isolated compounds, though the findings are preliminary. The root bark yielded a new oleanane-triterpene and a known quinone-methide triterpene, while the stem produced 21 triterpenes; however, no significant cytotoxic activity was reported for these. Additionally, Siphonodon celastrineus fruits provided ten poly-O-acylated β-dihydroagarofuran sesquiterpenoids, with siphonagarofuran J showing moderate cytotoxicity. To date, there are no major safety concerns or recorded drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Siphonodon celastrineus showed high cytotoxic activity against some cancer cell lines in vitro, but results are preliminary.
- A new oleanane-triterpene and a known quinone-methide triterpene were isolated from the root bark of Siphonodon celastrineus.
- Twenty-one triterpenes were isolated from the stem of Siphonodon celastrineus, and their structures characterized, but no significant cytotoxic activity was reported.
- Siphonodon celastrineus fruits yielded ten poly-O-acylated β-dihydroagarofuran sesquiterpenoids, with siphonagarofuran J showing moderate cytotoxic activity.
- Twenty polyoxygenated triterpenes were identified in Siphonodon celastrineus, including three with a rare 13,27-cyclopropane ring.
Frequently asked questions
What is Siphonodon celastrineus?
Siphonodon celastrineus (Siphonodon celastrineus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Siphonodon celastrineus?
5 sourced findings are recorded for Siphonodon celastrineus; the strongest carries evidence grade D. For example: Siphonodon celastrineus showed high cytotoxic activity against some cancer cell lines in vitro, but results are preliminary.
How strong is the evidence for Siphonodon celastrineus?
The strongest finding for Siphonodon celastrineus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Siphonodon celastrineus safe? What are the side effects?
No major safety issues are recorded for Siphonodon celastrineus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Siphonodon celastrineus interact with medications?
No drug interactions are recorded for Siphonodon celastrineus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Siphonodon celastrineus?
Siphonodon celastrineus is also known as: Сифонодон бересклетовый.
Is Siphonodon celastrineus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer. literature abstract metadata
- T2 Potentially cytotoxic triterpenoids from the root bark of Siphonodon celastrineus Griff. literature abstract metadata
- T2 Lupane, friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. literature abstract metadata
- T2 Polyoxygenated ursane and oleanane triterpenes from Siphonodon celastrineus. literature abstract metadata
- T2 Siphonagarofurans A-J: Poly-O-acylated β-dihydroagarofuran sesquiterpenoids from the fruits of Siphonodon celastrineus. literature abstract metadata