Solanum lyratum
Solanum lyratum
Solanum lyratum is a plant traditionally used with limited recorded practices. Scientific studies have shown significant anti-inflammatory activity, with compound 4 isolating at low concentrations. The metal-free bio-nanozyme derived from S. lyratum demonstrated synergistic tumor therapeutic effects through cascaded enzyme-like activities and photothermal enhancement. Additionally, Baiying Juhua Decoction containing S. lyratum steroidal alkaloids was found to inhibit non-small cell lung cancer progression via anti-angiogenic mechanisms and showed dual-targeted blocking effects on the IL-17A/STAT3 axis in HaCaT cells, potentially supporting its use for psoriasis treatment. No major safety issues or drug interactions have been recorded thus far.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- S. lyratum steroidal alkaloids showed dual-targeted blocking effects on the IL-17A/STAT3 axis in HaCaT cells, potentially supporting its use for psoriasis treatment.
- Solanum lyratum showed significant anti-inflammatory activity through screening, with compound 4 isolating at low concentrations.
- The study found that a metal-free bio-nanozyme derived from Solanum lyratum showed synergistic tumor therapeutic effects through cascaded enzyme-like activities and photothermal enhancement.
- The study found that Baiying Juhua Decoction inhibits non-small cell lung cancer progression through anti-angiogenic effects.
Frequently asked questions
What is Solanum lyratum?
Solanum lyratum (Solanum lyratum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Solanum lyratum?
4 sourced findings are recorded for Solanum lyratum; the strongest carries evidence grade D. For example: S. lyratum steroidal alkaloids showed dual-targeted blocking effects on the IL-17A/STAT3 axis in HaCaT cells, potentially supporting its use for psoriasis treatment.
How strong is the evidence for Solanum lyratum?
The strongest finding for Solanum lyratum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Solanum lyratum safe? What are the side effects?
No major safety issues are recorded for Solanum lyratum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Solanum lyratum interact with medications?
No drug interactions are recorded for Solanum lyratum in our sources. This does not rule them out — check with a pharmacist.
Is Solanum lyratum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Network pharmacology-based elucidation of the regulatory mechanism of Solanum lyratum (Bai Ying) against psoriasis via the IL-17A/STAT3 axis: Molecular docking and HaCaT cell validation. literature abstract metadata
- T2 Anti-angiogenesis effect of Baiying Juhua Decoction on the non-small cell lung cancer: integrating pharmacology, multi-machine learning and experimental investigation. literature abstract metadata
- T2 Solanum lyratum-derived metal-free bio-nanozyme for photothermally self-enhanced cascade catalytic synergistic tumor therapy. literature abstract metadata
- T2 Quantitative screening of anti-inflammatory components from a traditional Chinese medicine from Solanum lyratum Thunb. literature abstract metadata