Stemona
Stemona
Stemona is a traditional Chinese medicinal plant. Its use in herbal medicine traditions is not extensively documented. Scientific evidence indicates that Stemona tuberosa has potential applications, including genetic research and treating lung injuries through its alkaloids. In vitro studies suggest (-)-isostemonamine may have antiproliferative effects on certain breast cancer cells. Additionally, the plant shows promise as an anticoccidial agent by improving intestinal barrier integrity and altering gut microbiota. No significant safety concerns or known drug interactions have been reported to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study presents the first telomere-to-telomere genome assembly for Stemona tuberosa, providing a valuable reference for genetic research.
- Stemona alkaloids alleviated lung injury symptoms and restored sphingolipid levels in mice.
- (-)-isostemonamine exhibited potent antiproliferative activity against ERα-negative breast cancer cells.
- Stemona tuberosa ethanol extract showed significant in vitro and in vivo anticoccidial activity, improving intestinal barrier integrity and altering gut microbiota.
Frequently asked questions
What is Stemona?
Stemona (Stemona) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Stemona?
4 sourced findings are recorded for Stemona; the strongest carries evidence grade D. For example: The study presents the first telomere-to-telomere genome assembly for Stemona tuberosa, providing a valuable reference for genetic research.
How strong is the evidence for Stemona?
The strongest finding for Stemona carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Stemona safe? What are the side effects?
No major safety issues are recorded for Stemona in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Stemona interact with medications?
No drug interactions are recorded for Stemona in our sources. This does not rule them out — check with a pharmacist.
Is Stemona a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Investigation of the Protective Effect of Stemona Alkaloids on Acute Lung Injury via LC-MS/MS-Based Sphingolipid Metabolomic Profiling. literature abstract metadata
- T2 Anticoccidial activity and its potential Mechanisms of Stemona tuberosa against Eimeria tenella: In Vivo and In Vitro Investigations and Host Intestinal Protection. literature abstract metadata
- T2 A telomere-to-telomere reference genome for Stemona tuberosa. literature abstract metadata
- T2 [Synthesis of Functional Molecules for the Control of Biomolecular Functions]. literature abstract metadata