Tanacetum microphyllum
Tanacetum microphyllum
Tanacetum microphyllum, commonly known as small-flowered tansy, is an herb traditionally used in some regional practices but lacks specific documented traditional uses. Scientific evidence suggests that various flavonoids from this plant can suppress inflammatory markers such as iNOS and COX-2 expression, and inhibit nitric oxide and PGE2 production in macrophages, with some compounds also reducing TNF-alpha levels. Notably, most compounds did not significantly affect arachidonic acid metabolism but showed anti-inflammatory effects in a mouse ear model. Safety data for Tanacetum microphyllum indicate no major issues have been recorded, and there are currently no reported drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Various flavonoids from Tanacetum microphyllum suppressed LPS-induced iNOS and COX-2 expression in RAW 264.7 cells.
- Four flavonoids and one sesquiterpene lactone from Tanacetum microphyllum significantly inhibited LPS-induced nitric oxide and PGE2 production in macrophages, with two compounds also reducing TNF-alpha.
- Most extracted compounds from Tanacetum microphyllum showed no significant effect on arachidonic acid metabolism, but some flavonoids and a sesquiterpene lactone inhibited TXB2 release in platelets.
- Two flavonoids from Tanacetum microphyllum showed anti-inflammatory effects in a mouse ear model.
Frequently asked questions
What is Tanacetum microphyllum?
Tanacetum microphyllum (Tanacetum microphyllum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Tanacetum microphyllum?
4 sourced findings are recorded for Tanacetum microphyllum; the strongest carries evidence grade D. For example: Various flavonoids from Tanacetum microphyllum suppressed LPS-induced iNOS and COX-2 expression in RAW 264.7 cells.
How strong is the evidence for Tanacetum microphyllum?
The strongest finding for Tanacetum microphyllum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Tanacetum microphyllum safe? What are the side effects?
No major safety issues are recorded for Tanacetum microphyllum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Tanacetum microphyllum interact with medications?
No drug interactions are recorded for Tanacetum microphyllum in our sources. This does not rule them out — check with a pharmacist.
Is Tanacetum microphyllum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages. literature abstract metadata
- T2 Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum. literature abstract metadata
- T2 Isolation of two flavonoids from Tanacetum microphyllum as PMA-induced ear edema inhibitors. literature abstract metadata
- T2 Effects of compounds extracted from Tanacetum microphyllum on arachidonic acid metabolism in cellular systems. literature abstract metadata