Tiliacora triandra
Tiliacora triandra
Tiliacora triandra is a traditional plant with origins in Southeast Asia. While its specific uses within traditional medicine have not been extensively documented, studies have shown promising results for certain applications. Scientific evidence indicates that leaf extracts of Tiliacora triandra can ameliorate memory deficits and reduce neuroinflammatory responses in rats, suggesting potential benefits for cognitive health. Additionally, pectolinarigenin from the plant has demonstrated significant anti-cancer activity by inducing cell cycle arrest, apoptosis, and inhibiting MAPK signaling pathways. Another combination supplement, HMB-123, which includes Tiliacora triandra along with Ha-rak, Piper betle, and Garcinia mangostana, showed high anti-allergic, anti-inflammatory, and antimicrobial activities in vitro. However, the evidence for its use in alleviating symptoms of long COVID is preliminary, with larger clinical trials needed to confirm these findings. No major safety concerns or known drug interactions have been recorded for Tiliacora triandra; however, further research is warranted to fully understand its potential benefits and applications.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- HMB-123, a combination of Ha-rak, Piper betle, and Garcinia mangostana extracts, showed the highest anti-allergic, anti-inflammatory, and antimicrobial activities among tested combinations.
- Pectolinarigenin from Tiliacora triandra showed potent anti-cancer activity in triple-negative breast cancer cells by affecting cell cycle progression, inducing apoptosis, and inhibiting MAPK signaling.
- Tiliacora triandra leaf extract showed significant amelioration of LPS-induced memory deficits and reduced neuroinflammatory responses in rats.
- The CPE supplement showed potential in alleviating moderate to severe long COVID symptoms, particularly fatigue and post-exertional malaise, but larger trials are needed.
- The study found that feeding broiler chickens a phytosynbiotic containing Pediococcus acidilactici V202 and Tiliacora triandra leaf extract improved growth performance and gut health.
Frequently asked questions
What is Tiliacora triandra?
Tiliacora triandra (Tiliacora triandra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Tiliacora triandra?
5 sourced findings are recorded for Tiliacora triandra; the strongest carries evidence grade B. For example: HMB-123, a combination of Ha-rak, Piper betle, and Garcinia mangostana extracts, showed the highest anti-allergic, anti-inflammatory, and antimicrobial activities among tested combinations.
How strong is the evidence for Tiliacora triandra?
The strongest finding for Tiliacora triandra carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Tiliacora triandra safe? What are the side effects?
No major safety issues are recorded for Tiliacora triandra in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Tiliacora triandra interact with medications?
No drug interactions are recorded for Tiliacora triandra in our sources. This does not rule them out — check with a pharmacist.
Is Tiliacora triandra a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Impact of combined plant extracts on long COVID: An exploratory randomized controlled trial. literature abstract metadata
- T2 In vitro biological activities of a combination of Ha-rak remedy, Piper betle, and Garcinia mangostana for the treatment of atopic dermatitis. literature abstract metadata
- T2 Phytosynbiotic Containing Double-Layer Microencapsulated Pediococcus acidilactici V202 and Tiliacora triandra Leaf Extract Improve Growth Performance and Gut Health in Broiler Chickens. literature abstract metadata
- T2 Pectolinarigenin from Tiliacora triandra Exhibits Potent Anticancer Activity in Triple-Negative Breast Cancer Cells Through Cell Cycle Arrest, Apoptosis, and MAPK Signaling Inhibition. literature abstract metadata
- T2 Neuroprotective effects of Tiliacora triandra (Colebr.) Diels leaf extract against lipopolysaccharide-induced memory impairment via anti-neuroinflammation. literature abstract metadata