Tiliacora triandra
Tiliacora triandra
Tiliacora triandra is a plant traditionally not associated with any specific medicinal uses. Scientific evidence suggests that HMB-123, which includes extracts from Tiliacora triandra along with Ha-rak and Piper betle, exhibits strong anti-allergic, anti-inflammatory, and antimicrobial properties. Additionally, pectolinarigenin from the plant has shown potent anti-cancer activity in triple-negative breast cancer cells through mechanisms involving cell cycle progression, apoptosis induction, and MAPK signaling inhibition. Tiliacora triandra leaf extract also demonstrated significant improvement in memory deficits and reduced neuroinflammatory responses in rats subjected to LPS-induced conditions. The CPE supplement derived from the plant showed potential for alleviating symptoms of moderate to severe long COVID, particularly fatigue and post-exertional malaise; however, further large-scale trials are required to confirm these findings. No major safety concerns or known drug interactions have been recorded with Tiliacora triandra.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- HMB-123, a combination of Ha-rak, Piper betle, and Garcinia mangostana extracts, showed the highest anti-allergic, anti-inflammatory, and antimicrobial activities among tested combinations.
- Pectolinarigenin from Tiliacora triandra showed potent anti-cancer activity in triple-negative breast cancer cells by affecting cell cycle progression, inducing apoptosis, and inhibiting MAPK signaling.
- Tiliacora triandra leaf extract showed significant amelioration of LPS-induced memory deficits and reduced neuroinflammatory responses in rats.
- The CPE supplement showed potential in alleviating moderate to severe long COVID symptoms, particularly fatigue and post-exertional malaise, but larger trials are needed.
- The study found that feeding broiler chickens a phytosynbiotic containing Pediococcus acidilactici V202 and Tiliacora triandra leaf extract improved growth performance and gut health.
Frequently asked questions
What is Tiliacora triandra?
Tiliacora triandra (Tiliacora triandra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Tiliacora triandra?
5 sourced findings are recorded for Tiliacora triandra; the strongest carries evidence grade B. For example: HMB-123, a combination of Ha-rak, Piper betle, and Garcinia mangostana extracts, showed the highest anti-allergic, anti-inflammatory, and antimicrobial activities among tested combinations.
How strong is the evidence for Tiliacora triandra?
The strongest finding for Tiliacora triandra carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Tiliacora triandra safe? What are the side effects?
No major safety issues are recorded for Tiliacora triandra in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Tiliacora triandra interact with medications?
No drug interactions are recorded for Tiliacora triandra in our sources. This does not rule them out — check with a pharmacist.
Is Tiliacora triandra a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Impact of combined plant extracts on long COVID: An exploratory randomized controlled trial. literature abstract metadata
- T2 In vitro biological activities of a combination of Ha-rak remedy, Piper betle, and Garcinia mangostana for the treatment of atopic dermatitis. literature abstract metadata
- T2 Phytosynbiotic Containing Double-Layer Microencapsulated Pediococcus acidilactici V202 and Tiliacora triandra Leaf Extract Improve Growth Performance and Gut Health in Broiler Chickens. literature abstract metadata
- T2 Pectolinarigenin from Tiliacora triandra Exhibits Potent Anticancer Activity in Triple-Negative Breast Cancer Cells Through Cell Cycle Arrest, Apoptosis, and MAPK Signaling Inhibition. literature abstract metadata
- T2 Neuroprotective effects of Tiliacora triandra (Colebr.) Diels leaf extract against lipopolysaccharide-induced memory impairment via anti-neuroinflammation. literature abstract metadata