Tinospora cordifolia
Tinospora cordifolia
Tinospora cordifolia, commonly known as Indian gooseberry or heart-leaved moonseed, is a traditional plant used in Ayurveda and other Indian systems of medicine. It has been traditionally employed for digestive complaints and wound healing. Scientific evidence suggests that compounds from Tinospora cordifolia may potentially inhibit the African swine fever virus B175L protein, though more research is needed to confirm these findings. The plant also showed moderate DNA protective activity in some studies, with one metabolite, cordiside A, demonstrating significant inhibition of nitric oxide production without causing high cytotoxicity. Safety-wise, no major issues have been recorded, and there are currently no known drug interactions associated with Tinospora cordifolia.
- Traditionally for
- digestive complaints · wounds
- Traditions
- traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
What the science says
- The study identified two diketopiperazines from Streptomyces triticiradicis TTCF1 that showed potent antibacterial and selective cytotoxic activity against cancer cell lines.
- The study found that Tinospora cordifolia exhibited moderate DNA protective activity among the tested Himalayan species.
- Cordiside A (5) significantly inhibited nitric oxide, IL-6, and TNF-α production in macrophage cells with low cytotoxicity.
- The study suggests that several compounds from Tinospora cordifolia may potentially inhibit African swine fever virus B175L protein.
- TCAE, SLAE, and SPAE induced THP-1 cell apoptosis, suggesting potential therapeutic effects for leukemia, though more clinical studies are required.
Frequently asked questions
What is Tinospora cordifolia?
Tinospora cordifolia (Tinospora cordifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Tinospora cordifolia traditionally used for?
Traditional sources record Tinospora cordifolia for: digestive complaints, wounds. This reflects traditional use, not a proven medical treatment.
Which traditions use Tinospora cordifolia?
Tinospora cordifolia appears in these traditions in our sources: traditional.
What does the scientific evidence say about Tinospora cordifolia?
5 sourced findings are recorded for Tinospora cordifolia; the strongest carries evidence grade D. For example: The study identified two diketopiperazines from Streptomyces triticiradicis TTCF1 that showed potent antibacterial and selective cytotoxic activity against cancer cell lines.
How strong is the evidence for Tinospora cordifolia?
The strongest finding for Tinospora cordifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Tinospora cordifolia safe? What are the side effects?
No major safety issues are recorded for Tinospora cordifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Tinospora cordifolia interact with medications?
No drug interactions are recorded for Tinospora cordifolia in our sources. This does not rule them out — check with a pharmacist.
Is Tinospora cordifolia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Harnessing the potential of selected Himalayan species for phyto-cosmeceutical formulations guided through biochemometric analysis. literature abstract metadata
- T2 Diketopiperazines from the Endophytic Streptomyces triticiradicis TTCF1 (Tinospora cordifolia): Isolation and Evaluation of Antibacterial and Anticancer Properties. literature abstract metadata
- T2 Structurally Diverse Secondary Metabolites from the Stem of Tinospora cordifolia and Their Anti-Inflammatory Potential on RAW264.7 Macrophages. literature abstract metadata
- T2 In silico pharmacological analysis of Tinospora cordifolia compounds targeting African swine fever virus B175L. literature abstract metadata
- T2 Study of Tinospora cordifolia stem and Senna siamea leaf and pods: An in vitro therapeutic approach for leukemia. literature abstract metadata
- T3 Tinospora cordifolia CC BY-SA 4.0