Annual Devilthorn
Tribulus terrestris
Tribulus terrestris, commonly known as puncturevine or goat's rue, is a traditional plant used in Ayurveda and Unani medicine. It has been traditionally employed for enhancing male sexual performance and energy, as well as treating urinary disorders and skin conditions. Scientific evidence is limited but suggests potential benefits; a case report indicates the need for medical supervision when using herbal medications due to the risk of acute kidney injury. Animal studies have shown effective antimicrobial activity and accelerated wound healing with polyherbal green-synthesized silver nanoparticles gel, while Tribulus terrestris extract demonstrated reduced hormonal and oxidative markers in rats with polycystic ovary syndrome (PCOS), though further human trials are required to confirm these findings. The plant contains 67 identified compounds and 73 absorbed constituents/metabolites, which may predict involvement of the PI3K/AKT signaling pathway in ischemic stroke-related processes. No major safety issues or drug interactions have been recorded for Tribulus terrestris; however, further research is necessary to fully understand its effects and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This case report highlights the potential risk of Tribulus terrestris in causing acute kidney injury, emphasizing the need for medical supervision with herbal medication use.
- The study found that polyherbal green-synthesized silver nanoparticles gel showed effective antimicrobial activity and accelerated wound healing in an animal model.
- Tribulus terrestris extract showed reduced hormonal and oxidative markers in PCOS rats, but further human studies are needed.
- Tribulus terrestris ethanol extract showed no sub-acute toxicity and exhibited significant antiurolithiatic activity in rats.
- This study identified 67 compounds in Tribulus terrestris L. extract and 73 absorbed constituents/metabolites, predicting potential involvement of the PI3K/AKT signaling pathway in ischemic stroke-related processes.
Frequently asked questions
What is Annual Devilthorn?
Annual Devilthorn (Tribulus terrestris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Annual Devilthorn?
5 sourced findings are recorded for Annual Devilthorn; the strongest carries evidence grade D. For example: This case report highlights the potential risk of Tribulus terrestris in causing acute kidney injury, emphasizing the need for medical supervision with herbal medication use.
How strong is the evidence for Annual Devilthorn?
The strongest finding for Annual Devilthorn carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Annual Devilthorn safe? What are the side effects?
No major safety issues are recorded for Annual Devilthorn in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Annual Devilthorn interact with medications?
No drug interactions are recorded for Annual Devilthorn in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Annual Devilthorn?
Annual Devilthorn is also known as: Якорцы стелющиеся, Tribule terrestre.
Is Annual Devilthorn a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Polyherbal green-synthesised silver nanoparticle gel: in vitro antimicrobial activity and in vivo wound healing efficacy using mimosa pudica and tribulus terrestris extracts. literature abstract metadata
- T2 Effect of Tribulus terrestris L. extract in the management of polycystic ovarian syndrome in rat model. literature abstract metadata
- T2 Sub-Acute Toxicity Evaluation and Antiurolithiatic Activity of Tribulus terrestris Ethanol Extract in Rats. literature abstract metadata
- T2 The Effect of Tribulus Terrestris on Acute Kidney Injury: A Case Study. literature abstract metadata
- T2 Systematic profiling of chemical components in Tribulus terrestris L. extract and its absorbed parent compounds/metabolites in rat plasma utilizing UPLC-Q-TOF/MS. literature abstract metadata