Uvaria rufa
Uvaria rufa
Uvaria rufa is a plant native to Southeast Asia. Traditional uses of this plant are not well-documented, suggesting limited historical application in folk medicine or other traditional practices. Scientific studies have identified several bioactive compounds from Uvaria rufa, including acetogenins and flavonoids, which showed weak to moderate antimycobacterial and anti-inflammatory activities but were less effective against cancer cell lines. The research also highlighted the plant's potential antioxidant and anti-melanogenic properties, with some evidence indicating it may inhibit melanin production and tyrosinase activity. Safety concerns are currently minimal, as no significant adverse effects or major drug interactions have been reported.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Several compounds from Uvaria rufa showed weak to moderate antimycobacterial or anti-inflammatory activity, but were inactive against cancer cell lines.
- The study developed a method using LC-MS and molecular networking to identify acetogenins in Uvaria rufa extracts.
- Four new acetogenins and thirteen known ones were isolated from Uvaria rufa, showing varying cytotoxicity against certain human cancer cell lines.
- The ethanol extract of Uvaria rufa fruits showed antioxidant and anti-melanogenic effects, inhibiting melanin production and tyrosinase activity.
Frequently asked questions
What is Uvaria rufa?
Uvaria rufa (Uvaria rufa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Uvaria rufa?
4 sourced findings are recorded for Uvaria rufa; the strongest carries evidence grade D. For example: Several compounds from Uvaria rufa showed weak to moderate antimycobacterial or anti-inflammatory activity, but were inactive against cancer cell lines.
How strong is the evidence for Uvaria rufa?
The strongest finding for Uvaria rufa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Uvaria rufa safe? What are the side effects?
No major safety issues are recorded for Uvaria rufa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Uvaria rufa interact with medications?
No drug interactions are recorded for Uvaria rufa in our sources. This does not rule them out — check with a pharmacist.
Is Uvaria rufa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Polyoxygenated cyclohexene derivatives and other constituents of Uvaria rufa stem. literature abstract metadata
- T2 Acetogenins from the Stem of Uvaria rufa and Their Cytotoxic Activity. literature abstract metadata
- T2 Feature-based molecular networking and MS2LDA analysis for the dereplication of adjacent bis-tetrahydrofuran Annonaceous acetogenins. literature abstract metadata
- T2 The Effect of Uvaria rufa Fruit Extract for Antioxidant and Anti-Melanogenic Activities and Phytochemical Profiling Using LC-MS Analysis. literature abstract metadata