Vaccinium dunalianum
Vaccinium dunalianum
Vaccinium dunalianum is a plant native to specific regions, though its traditional medicinal uses are not well-documented. Scientific studies have shown that leaf extracts from this plant, which contain high levels of caffeoylquinic acids, exhibit potent inhibitory effects on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with 1-O-caffeoylquinic acid being the most effective. Additionally, genomic analysis has revealed multiple biosynthesis gene clusters for secondary metabolites, though no significant differences were observed between valproic acid treatments. The plant also demonstrates moderate to potent antifungal activity against several tested phytopathogenic fungi, with five compounds exhibiting such properties. Notably, two new compounds and a unique meroterpenoid were isolated from an endophytic fungus associated with the plant, one of which showed broad-spectrum antifungal activity. To date, no major safety concerns or drug interactions have been recorded for Vaccinium dunalianum.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Vaccinium dunalianum leaf extracts, rich in caffeoylquinic acids, potently inhibit both AChE and BChE with 1-O-caffeoylquinic acid being the most effective.
- The genomic analysis identified multiple biosynthesis gene clusters for secondary metabolites, but no significant difference was observed between valproic acid treatments.
- Five compounds exhibited moderate to potent antifungal activity against five tested phytopathogenic fungi.
- Two new compounds and a unique meroterpenoid were isolated from an endophytic fungus, with one showing potent broad-spectrum antifungal activity.
Frequently asked questions
What is Vaccinium dunalianum?
Vaccinium dunalianum (Vaccinium dunalianum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Vaccinium dunalianum?
4 sourced findings are recorded for Vaccinium dunalianum; the strongest carries evidence grade D. For example: Vaccinium dunalianum leaf extracts, rich in caffeoylquinic acids, potently inhibit both AChE and BChE with 1-O-caffeoylquinic acid being the most effective.
How strong is the evidence for Vaccinium dunalianum?
The strongest finding for Vaccinium dunalianum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Vaccinium dunalianum safe? What are the side effects?
No major safety issues are recorded for Vaccinium dunalianum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Vaccinium dunalianum interact with medications?
No drug interactions are recorded for Vaccinium dunalianum in our sources. This does not rule them out — check with a pharmacist.
Is Vaccinium dunalianum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Two New Compounds Isolated From the Endophytic Fungus Guignardia Mangiferae VDL166 of Vaccinium Dunalianum. literature abstract metadata
- T2 Novel Antifungal Pyridine Alkaloids from Endophytic Fungus Penicillium citrinum VDL118. literature abstract metadata
- T2 Genomic features and the transcriptional regulation of secondary metabolite biosynthesis of endophytic fungus Xylaria sp. VDL4 isolated from Vaccinium dunalianum. literature abstract metadata
- T2 Molecular Mechanistic Studies on Caffeoylquinic Acid Derivatives From Vaccinium dunalianum Wight as Dual-Target Inhibitors of AChE and BChE With In Vitro Inhibitory Evaluation and Molecular Docking. literature abstract metadata