Ventilago denticulata
Ventilago denticulata
Ventilago denticulata is a plant traditionally used in certain regions but lacks specific traditional medicinal applications documented. Scientific evidence suggests that extracts from Ventilago denticulata may have potential, with moderate inhibition of CYP3A-mediated gefitinib metabolism and the isolation of new anthraquinones showing antiproliferative activity against some cancer cell lines. Additionally, nine antimicrobial agents were identified, including both known and novel compounds, indicating possible broad-spectrum biological activities such as cytotoxicity, antibacterial properties, antioxidant effects, and phosphodiesterase inhibition. To date, no significant safety concerns or drug interactions have been reported for Ventilago denticulata.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified nine antimicrobial agents in Ventilago denticulata, including known and new compounds.
- Ventilago denticulata extract moderately inhibited CYP3A-mediated gefitinib metabolism with an IC50 value of 7.06 ± 1.23 μg/mL.
- Four new anthraquinones were isolated from Ventilago denticulata roots, and one exhibited moderate antiproliferative activity against certain cancer cell lines.
- New compounds from Ventilago denticulata showed varying degrees of cytotoxic, antibacterial, antioxidant, and phosphodiesterase inhibitory activities.
Frequently asked questions
What is Ventilago denticulata?
Ventilago denticulata (Ventilago denticulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ventilago denticulata?
4 sourced findings are recorded for Ventilago denticulata; the strongest carries evidence grade D. For example: The study identified nine antimicrobial agents in Ventilago denticulata, including known and new compounds.
How strong is the evidence for Ventilago denticulata?
The strongest finding for Ventilago denticulata carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Ventilago denticulata safe? What are the side effects?
No major safety issues are recorded for Ventilago denticulata in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ventilago denticulata interact with medications?
No drug interactions are recorded for Ventilago denticulata in our sources. This does not rule them out — check with a pharmacist.
Is Ventilago denticulata a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Naphthalene Derivatives and Quinones from Ventilago denticulata and Their Nitric Oxide Radical Scavenging, Antioxidant, Cytotoxic, Antibacterial, and Phosphodiesterase Inhibitory Activities. literature abstract metadata
- T2 UHPLC-ESI-QTOF-MS/MS-Based Molecular Networking Guided Isolation and Dereplication of Antibacterial and Antifungal Constituents of Ventilago denticulata. literature abstract metadata
- T2 Four New Anthraquinones with Histone Deacetylase Inhibitory Activity from Ventilago denticulata Roots. literature abstract metadata
- T2 Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib. literature abstract metadata