Manchuria violet
Viola mandshurica
Viola mandshurica, a traditional medicine plant, has not been extensively documented for its specific uses in any particular tradition. Scientific evidence suggests that compounds from Viola mandshurica may have anti-inflammatory properties, as it significantly inhibited nitric oxide (NO) and prostaglandin E2 (PGE2) production and reduced inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression in RAW264.7 cells. Additionally, studies have isolated three novel Roseateles species from artificial pond water and Viola mandshurica root, as well as two novel Paenibacillus species from the roots of Suaeda japonica and Viola mandshurica, respectively. These findings also indicate potential anti-obesity effects in high-fat diet (HFD)-induced obese mice through mechanisms that suppress lipogenesis and activate AMP-activated protein kinase (AMPK). No major safety concerns or recorded drug interactions have been identified for this plant, though further research is warranted to fully understand its therapeutic applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- CEFV significantly inhibited NO and PGE2 production and reduced iNOS and COX-2 expression in RAW264.7 cells.
- Three novel Roseateles species, R. subflavus, R. aquae, and R. violae, were isolated from artificial pond water and Viola mandshurica root.
- Both VME and VMA from Viola mandshurica decreased body weight gain and lipid levels in HFD-induced obese mice, suggesting anti-obesity effects.
- Two novel Paenibacillus species, Paenibacillus suaedae and Paenibacillus violae, were isolated from Suaeda japonica and Viola mandshurica roots.
Frequently asked questions
What is Manchuria violet?
Manchuria violet (Viola mandshurica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Manchuria violet?
4 sourced findings are recorded for Manchuria violet; the strongest carries evidence grade D. For example: CEFV significantly inhibited NO and PGE2 production and reduced iNOS and COX-2 expression in RAW264.7 cells.
How strong is the evidence for Manchuria violet?
The strongest finding for Manchuria violet carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Manchuria violet safe? What are the side effects?
No major safety issues are recorded for Manchuria violet in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Manchuria violet interact with medications?
No drug interactions are recorded for Manchuria violet in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Manchuria violet?
Manchuria violet is also known as: Фиалка маньчжурская.
Is Manchuria violet a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-obesity activity, acute toxicity, and chemical constituents of aqueous and ethanol Viola mandshurica extracts. literature abstract metadata
- T2 Roseateles subflavus sp. nov. and Roseateles aquae sp. nov., isolated from artificial pond water and Roseateles violae sp. nov., isolated from a Viola mandshurica root. literature abstract metadata
- T2 Paenibacillus suaedae sp. nov. and Paenibacillus violae sp. nov., isolated from the roots of Suaeda japonica Makino and Viola mandshurica W. Becker with plant growth-promoting potential. literature abstract metadata
- T2 Chloroform Extract from Fermented Viola mandshurica Regulates LPS-Induced Inflammation Response in RAW 264.7 Cells by Inhibiting iNOS and COX-2. literature abstract metadata