Wolfiporia extensa

Wolfiporia extensa

Wolfiporia extensa, also known as Hoelen or Poria, is a traditional Chinese medicinal fungus. While its use in specific traditional practices has not been extensively documented, it has shown promise in various scientific studies. Research indicates that certain Chinese herbal medicines containing Wolfiporia extensa may improve sleep quality and effectiveness rates compared to conventional treatments for insomnia. Additionally, a combination of Crataegus pinnatifida and Wolfiporia extensa was found to enhance metabolic health and alter gut microbiota in mice on a high-fat diet. Network pharmacology and molecular docking studies suggest potential mechanisms for treating tremor-dominant Parkinson's disease. Furthermore, Wolfiporia extensa extract-loaded nanocomposites demonstrated enhanced antioxidant activity and promoted osteogenic differentiation and cell migration. To date, no major safety issues or drug interactions have been recorded with the use of this fungus.

At a glance
Best evidence
A
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Certain Chinese herbal medicines showed improvements in sleep quality, effectiveness rates, and safety profiles compared to conventional treatments for insomnia. A PMID
  • The study found that a combination of Crataegus pinnatifida and Wolfiporia extensa improved metabolic health and altered gut microbiota in mice fed a high-fat diet. D PMID
  • The study identified potential mechanisms of Wolfiporia extensa's components in treating tremor-dominant Parkinson's disease through network pharmacology and molecular docking. D PMID
  • Wolfiporia extensa extract-loaded nanocomposites showed enhanced antioxidant activity and promoted osteogenic differentiation and cell migration. D PMID

Frequently asked questions

What is Wolfiporia extensa?

Wolfiporia extensa (Wolfiporia extensa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Wolfiporia extensa?

4 sourced findings are recorded for Wolfiporia extensa; the strongest carries evidence grade A. For example: Certain Chinese herbal medicines showed improvements in sleep quality, effectiveness rates, and safety profiles compared to conventional treatments for insomnia.

How strong is the evidence for Wolfiporia extensa?

The strongest finding for Wolfiporia extensa carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Wolfiporia extensa safe? What are the side effects?

No major safety issues are recorded for Wolfiporia extensa in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Wolfiporia extensa interact with medications?

No drug interactions are recorded for Wolfiporia extensa in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Wolfiporia extensa?

Wolfiporia extensa is also known as: Pachyme.

Is Wolfiporia extensa a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Predictive Analysis of Yi-Gai-San's Multifaceted Mechanisms for Tremor-dominant Parkinson's Disease via Network Pharmacology and Molecular Docking Validation. literature abstract metadata
  2. T2 The Effects of Crataegus pinnatifida and Wolfiporia extensa Combination on Diet-Induced Obesity and Gut Microbiota. literature abstract metadata
  3. T2 Wolfiporia extensa Extract-Loaded Carboxymethyl Cellulose-Stabilized Cerium Oxide-Doped Hydroxyapatite Nanocomposites as Advanced Antioxidant Platform for Bone Tissue Regeneration. literature abstract metadata
  4. T2 Chinese herbal medicine for insomnia: A systematic review and network meta-analysis. literature abstract metadata