California mugwort
Artemisia douglasiana
Artemisia douglasiana is a plant traditionally found in North America. While it has not been extensively used in traditional medicine, studies have shown that dehydroleucodine, a compound derived from this plant, exhibited dose-dependent lethality to Bufo arenarum embryos and cytotoxicity against both normal human cells and breast cancer cell lines. Additionally, treatment with dehydroleucodine induced DNA damage leading to senescence or apoptosis in cancer cells. In mice, dehydroleucodine also delayed intestinal transit, which may be mediated through interaction with the α2-adrenergic receptor. No major safety issues or drug interactions have been recorded for Artemisia douglasiana; however, further research is needed to fully understand its potential effects and applications.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- Dehidrolevocodina mostró letalidad dependiente de la dosis en los embriones de Bufo arenarum, con concentraciones más altas siendo más perjudiciales.
- Extraídos etílicos y acuoso de Artemisia douglasiana mostraron citotoxicidad tanto en células humanas normales como en líneas celulares de cáncer de mama.
- Dehidroluquodina de Artemisia douglasiana retrasó el tránsito intestinal en ratones, potencialmente a través de la interacción con el receptor adrenérgico α2.
- El tratamiento con dehidroleucodina induce daño a DNA, senescencia o apoptosis en células cancerosas dependiendo de la concentración.
Frequently asked questions
What is California mugwort?
California mugwort (Artemisia douglasiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about California mugwort?
4 sourced findings are recorded for California mugwort; the strongest carries evidence grade D. For example: Dehidrolevocodina mostró letalidad dependiente de la dosis en los embriones de Bufo arenarum, con concentraciones más altas siendo más perjudiciales.
How strong is the evidence for California mugwort?
The strongest finding for California mugwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is California mugwort safe? What are the side effects?
No major safety issues are recorded for California mugwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does California mugwort interact with medications?
No drug interactions are recorded for California mugwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of California mugwort?
California mugwort is also known as: Полынь Дугласа, armoise de Douglas.
Is California mugwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Effect of dehydroleucodine on intestinal transit: structural basis of the interaction with the α(2)-adrenergic receptor. literature abstract metadata
- T2 Lethal effect of dehydroleucodine (DhL) on amphibian Bufo arenarum embryos. literature abstract metadata
- T2 The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers. literature abstract metadata
- T2 Ethanolic Extracts of California Mugwort (Artemisia douglasiana Besser) Are Cytotoxic against Normal and Cancerous Human Cells. literature abstract metadata