California mugwort
Artemisia douglasiana
Artemisia douglasiana 是一种传统上在美国北部，特别是美国西部发现的植物。尽管它在传统医学中的使用并不广泛，但研究表明从这种植物中提取的去氢莱库多因对 Bufo arenarum 的胚胎具有剂量依赖性毒性，较高浓度更为有害。乙醇和水提取物 Artemisia douglasiana 对正常人类细胞和乳腺癌细胞系均表现出细胞毒性，表明其可能具有抗肿瘤作用。此外，去氢莱库多因在小鼠中被发现会延迟肠道传输，可能是通过与α2-肾上腺素能受体相互作用实现的。使用不同浓度的去氢莱库多因治疗会导致癌细胞 DNA 损伤、衰老或凋亡。尚未记录该植物的重大安全问题，并且没有报告药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 去氢乌头原碱对Bufo arenarum胚胎表现出剂量依赖性毒性，较高浓度更为有害。
- 乙醇和水提取物的 Artemisia douglasiana 显示出对正常人类细胞和乳腺癌细胞系均有细胞毒性。
- 从 Artemisia douglasiana 中提取的去水乐可定延迟了小鼠的肠道传输，可能通过与α2-肾上腺素能受体相互作用实现。
- 使用去水龙胆碱治疗会根据浓度导致癌细胞发生DNA损伤、衰老或凋亡。
Frequently asked questions
What is California mugwort?
California mugwort (Artemisia douglasiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about California mugwort?
4 sourced findings are recorded for California mugwort; the strongest carries evidence grade D. For example: 去氢乌头原碱对Bufo arenarum胚胎表现出剂量依赖性毒性，较高浓度更为有害。
How strong is the evidence for California mugwort?
The strongest finding for California mugwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is California mugwort safe? What are the side effects?
No major safety issues are recorded for California mugwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does California mugwort interact with medications?
No drug interactions are recorded for California mugwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of California mugwort?
California mugwort is also known as: Полынь Дугласа, armoise de Douglas.
Is California mugwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Effect of dehydroleucodine on intestinal transit: structural basis of the interaction with the α(2)-adrenergic receptor. literature abstract metadata
- T2 Lethal effect of dehydroleucodine (DhL) on amphibian Bufo arenarum embryos. literature abstract metadata
- T2 The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers. literature abstract metadata
- T2 Ethanolic Extracts of California Mugwort (Artemisia douglasiana Besser) Are Cytotoxic against Normal and Cancerous Human Cells. literature abstract metadata