California mugwort
Artemisia douglasiana
Artemisia douglasiana is a plant traditionally found in North America. While it has not been extensively used in traditional medicine, studies have shown that dehydroleucodine, a compound derived from this plant, exhibited dose-dependent lethality to Bufo arenarum embryos and cytotoxicity against both normal human cells and breast cancer cell lines. Additionally, treatment with dehydroleucodine induced DNA damage leading to senescence or apoptosis in cancer cells. In mice, dehydroleucodine also delayed intestinal transit, which may be mediated through interaction with the α2-adrenergic receptor. No major safety issues or drug interactions have been recorded for Artemisia douglasiana; however, further research is needed to fully understand its potential effects and applications.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 去氢乌头原碱对Bufo arenarum胚胎表现出剂量依赖性毒性，较高浓度更为有害。
- 乙醇和水提取物的 Artemisia douglasiana 显示出对正常人类细胞和乳腺癌细胞系均有细胞毒性。
- 从 Artemisia douglasiana 中提取的去水乐可定延迟了小鼠的肠道传输，可能通过与α2-肾上腺素能受体相互作用实现。
- 使用去水龙胆碱治疗会根据浓度导致癌细胞发生DNA损伤、衰老或凋亡。
Frequently asked questions
What is California mugwort?
California mugwort (Artemisia douglasiana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about California mugwort?
4 sourced findings are recorded for California mugwort; the strongest carries evidence grade D. For example: 去氢乌头原碱对Bufo arenarum胚胎表现出剂量依赖性毒性，较高浓度更为有害。
How strong is the evidence for California mugwort?
The strongest finding for California mugwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is California mugwort safe? What are the side effects?
No major safety issues are recorded for California mugwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does California mugwort interact with medications?
No drug interactions are recorded for California mugwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of California mugwort?
California mugwort is also known as: Полынь Дугласа, armoise de Douglas.
Is California mugwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Effect of dehydroleucodine on intestinal transit: structural basis of the interaction with the α(2)-adrenergic receptor. literature abstract metadata
- T2 Lethal effect of dehydroleucodine (DhL) on amphibian Bufo arenarum embryos. literature abstract metadata
- T2 The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers. literature abstract metadata
- T2 Ethanolic Extracts of California Mugwort (Artemisia douglasiana Besser) Are Cytotoxic against Normal and Cancerous Human Cells. literature abstract metadata