Clerodendrum petasites
Clerodendrum petasites
Clerodendrum petasites is a traditional plant used primarily in Asian medicine, particularly in China and Japan. It has been traditionally employed for various health conditions but specific uses are not well-documented. Scientific studies have shown that topical formulations of Clerodendrum petasites extracts can deliver phenolic compounds such as vanillic acid, nepetin, and hispidulin to the skin, indicating potential dermal benefits. These extracts also demonstrated significant antinociceptive and anti-inflammatory effects without apparent central nervous system (CNS) side effects at tested doses. In vitro studies with cell lines showed that CpEA and hesperetin from Clerodendrum petasites have potent anti-inflammatory properties by reducing cytokine release and inhibiting inflammatory gene expressions, suggesting potential therapeutic applications. Additionally, the combination of Clerodendrum petasites with other plants has shown promise in anti-allergic, anti-inflammatory, and antimicrobial activities, though further research is necessary to validate these findings. No major safety concerns or recorded drug interactions have been identified for Clerodendrum petasites.
- Mejor evidencia
- B
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- Formulaciones tópicas de los extractos de Clerodendrum petasites mostraron una entrega variable de compuestos fenólicos, con la detección de ácido vanilico, nepetina y hispidulina en el estrato cornificado.
- El extracto de Clerodendrum petasites mostró efectos antinociceptivos y antiinflamatorios significativos sin impactos adversos en el sistema nervioso central a dosis probadas.
- CpEA y hesperetina de Clerodendrum petasites mostraron propiedades antiinflamatorias mayores al reducir la liberación de citocinas e inhibir las expresiones genéticas inflamatorias en células A549.
- La combinación de Clerodendrum petasites y otras plantas mostró posibles actividades antialérgicas, antiinflamatorias y antimicrobianas in vitro.
Frequently asked questions
What is Clerodendrum petasites?
Clerodendrum petasites (Clerodendrum petasites) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Clerodendrum petasites?
4 sourced findings are recorded for Clerodendrum petasites; the strongest carries evidence grade B. For example: Formulaciones tópicas de los extractos de Clerodendrum petasites mostraron una entrega variable de compuestos fenólicos, con la detección de ácido vanilico, nepetina y hispidulina en el estrato cornificado.
How strong is the evidence for Clerodendrum petasites?
The strongest finding for Clerodendrum petasites carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Clerodendrum petasites safe? What are the side effects?
No major safety issues are recorded for Clerodendrum petasites in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Clerodendrum petasites interact with medications?
No drug interactions are recorded for Clerodendrum petasites in our sources. This does not rule them out — check with a pharmacist.
Is Clerodendrum petasites a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Topical formulation and dermal delivery of active phenolic compounds in the Thai medicinal plant--Clerodendrum petasites S. Moore. literature abstract metadata
- T2 Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells via Modulation of the Akt/MAPK/AP-1 Pathway. literature abstract metadata
- T2 Antinociceptive efficacy of Clerodendrum petasites S. Moore, a Thai medicinal plant, and its CNS safety profiles. literature abstract metadata
- T2 In vitro biological activities of a combination of Ha-rak remedy, Piper betle, and Garcinia mangostana for the treatment of atopic dermatitis. literature abstract metadata