Clerodendrum petasites

Clerodendrum petasites

Clerodendrum petasites 是一种传统上在各种草药实践中使用的植物,但缺乏具体的文献记录用途。科学研究表明,其提取物的外用制剂可以将如 vanillic 酸、nepetin 和 hispidulin 等酚类化合物递送到皮肤中,显示出潜在的皮肤益处。Clerodendrum petasites 在测试剂量下表现出显著的抗痛觉过敏和抗炎作用,而不会对中枢神经系统产生不良影响。实验室研究还表明,该植物中的化合物如 CpEA 和 hesperetin 具有强大的抗炎作用,通过减少细胞培养中细胞因子的释放并抑制炎症基因表达来实现。将 Clerodendrum petasites 与其他植物结合使用显示出潜在的抗过敏、抗炎和抗菌活性。迄今为止,尚未记录重大安全问题或药物相互作用,但进一步的研究对于完全了解其效果及其应用是必要的。

速览
最佳证据
B
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • Clerodendrum petasites 提取物的外用制剂显示出酚类化合物在皮肤中的变量递送,检测到 vanillic 酸、nepetin 和 hispidulin 在角质层中。 B PMID
  • Clerodendrum petasites 提取物在测试剂量下显示出显著的镇痛和抗炎作用,且未见对中枢神经系统(CNS)的不良影响。 D PMID
  • 从铁线莲中提取的CpEA和橙皮苷在A549细胞中通过减少细胞因子释放和抑制炎症基因表达显示出更强的抗炎作用。 D PMID
  • Clerodendrum petasites 和其他植物的组合在体外显示出潜在的抗过敏、抗炎和抗菌活性。 D PMID

Frequently asked questions

What is Clerodendrum petasites?

Clerodendrum petasites (Clerodendrum petasites) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Clerodendrum petasites?

4 sourced findings are recorded for Clerodendrum petasites; the strongest carries evidence grade B. For example: Clerodendrum petasites 提取物的外用制剂显示出酚类化合物在皮肤中的变量递送,检测到 vanillic 酸、nepetin 和 hispidulin 在角质层中。

How strong is the evidence for Clerodendrum petasites?

The strongest finding for Clerodendrum petasites carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Clerodendrum petasites safe? What are the side effects?

No major safety issues are recorded for Clerodendrum petasites in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Clerodendrum petasites interact with medications?

No drug interactions are recorded for Clerodendrum petasites in our sources. This does not rule them out — check with a pharmacist.

Is Clerodendrum petasites a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Topical formulation and dermal delivery of active phenolic compounds in the Thai medicinal plant--Clerodendrum petasites S. Moore. literature abstract metadata
  2. T2 Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells via Modulation of the Akt/MAPK/AP-1 Pathway. literature abstract metadata
  3. T2 Antinociceptive efficacy of Clerodendrum petasites S. Moore, a Thai medicinal plant, and its CNS safety profiles. literature abstract metadata
  4. T2 In vitro biological activities of a combination of Ha-rak remedy, Piper betle, and Garcinia mangostana for the treatment of atopic dermatitis. literature abstract metadata