Angular Winter-cherry
Physalis angulata
Physalis angulata, comúnmente conocida como fresas del suelo o fruta de oro, es una planta tradicionalmente utilizada en diversas culturas pero que carece de usos medicinales tradicionales documentados. Un análisis de 239 plantas medicinales de varios grupos étnicos en Indonesia resaltó debilidades metodológicas, lo que hace que las conclusiones definitivas sean difíciles. Se han demostrado que la escasez hídrica puede alterar las respuestas fisiológicas de Physalis angulata, incluyendo cambios en el estado hidráulico y intercambio gaseoso. Los withanoloides extraídos del planta mostraron actividad antimalárgica potente tanto in vitro como in vivo al activar la vía p53. La seguridad actualmente no ha generado preocupaciones, con un registro de problemas menores. De manera similar, no hay evidencia de interacciones significativas entre los fármacos y Physalis angulata.
- Mejor evidencia
- A
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- The study identified withanolides from Physalis angulata that inhibit melanoma cell proliferation and tumor growth in mice by activating the p53 pathway.
- El estudio identificó un núcleo común de 239 especies de plantas medicinales en múltiples grupos étnicos en Indonesia, aunque la evaluación de calidad resaltó debilidades metodológicas.
- PA interfiere con el progreso del ciclo celular en células escamosas de carcinoma oral humanas a través de la señalización de topoisomerasa II/ATM/ATR/Chk para el arresto en la fase G2/M.
- Water deficit induced changes in Physalis angulata's water status, gas exchange, and accumulation of organic solutes, with varying responses depending on the duration of stress.
Frequently asked questions
What is Angular Winter-cherry?
Angular Winter-cherry (Physalis angulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Angular Winter-cherry?
4 sourced findings are recorded for Angular Winter-cherry; the strongest carries evidence grade A. For example: The study identified withanolides from Physalis angulata that inhibit melanoma cell proliferation and tumor growth in mice by activating the p53 pathway.
How strong is the evidence for Angular Winter-cherry?
The strongest finding for Angular Winter-cherry carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Angular Winter-cherry safe? What are the side effects?
No major safety issues are recorded for Angular Winter-cherry in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Angular Winter-cherry interact with medications?
No drug interactions are recorded for Angular Winter-cherry in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Angular Winter-cherry?
Angular Winter-cherry is also known as: Coqueret.
Is Angular Winter-cherry a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Withanolides from Physalis angulata as Potent Antimelanoma Agents: Activation of the p53 Pathway In Vitro and In Vivo. literature abstract metadata
- T2 Physalin A interferes with cell cycle in human oral squamous carcinoma cells via DNA topoisomerase II/ATM/ATR/Chk signaling for G2/M phase arrest. literature abstract metadata
- T2 A systematic review of ethnobotanical study in Indonesia: diversity and cultural patterns of medicinal plant use. literature abstract metadata
- T2 Water deficit exposure: physiological and biochemical changes in Physalis angulata L. (Solanaceae). literature abstract metadata