Angular Winter-cherry
Physalis angulata
Physalis angulata，通常被称为地梅子或金果莓，是一种在多种文化中传统使用的植物，但缺乏具体的传统医学用途记录。对印度尼西亚多个民族群体中的239种药用植物进行的审查指出了方法学上的不足之处，使得得出明确结论变得困难。实验室研究表明，水分短缺可以改变Physalis angulata的生理反应，包括水状态和气体交换的变化。从该植物中提取的withanolides在体外和体内均表现出强大的抗黑色素瘤活性，并通过激活p53途径发挥作用。目前尚未报告安全问题，也没有记录到重大问题。同样，没有证据表明与Physalis angulata相关的显著药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- The study identified withanolides from Physalis angulata that inhibit melanoma cell proliferation and tumor growth in mice by activating the p53 pathway.
- 该审查在印度尼西亚多个民族群体中识别出了239种常用药用植物的核心，但质量评估强调了方法学上的缺陷。
- PA通过DNA拓扑异构酶II/ATM/ATR/Chk信号通路干扰人类口腔鳞状细胞癌细胞的细胞周期进程，使其在G2/M期停滞。
- Water deficit induced changes in Physalis angulata's water status, gas exchange, and accumulation of organic solutes, with varying responses depending on the duration of stress.
Frequently asked questions
What is Angular Winter-cherry?
Angular Winter-cherry (Physalis angulata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Angular Winter-cherry?
4 sourced findings are recorded for Angular Winter-cherry; the strongest carries evidence grade A. For example: The study identified withanolides from Physalis angulata that inhibit melanoma cell proliferation and tumor growth in mice by activating the p53 pathway.
How strong is the evidence for Angular Winter-cherry?
The strongest finding for Angular Winter-cherry carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Angular Winter-cherry safe? What are the side effects?
No major safety issues are recorded for Angular Winter-cherry in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Angular Winter-cherry interact with medications?
No drug interactions are recorded for Angular Winter-cherry in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Angular Winter-cherry?
Angular Winter-cherry is also known as: Coqueret.
Is Angular Winter-cherry a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Withanolides from Physalis angulata as Potent Antimelanoma Agents: Activation of the p53 Pathway In Vitro and In Vivo. literature abstract metadata
- T2 Physalin A interferes with cell cycle in human oral squamous carcinoma cells via DNA topoisomerase II/ATM/ATR/Chk signaling for G2/M phase arrest. literature abstract metadata
- T2 A systematic review of ethnobotanical study in Indonesia: diversity and cultural patterns of medicinal plant use. literature abstract metadata
- T2 Water deficit exposure: physiological and biochemical changes in Physalis angulata L. (Solanaceae). literature abstract metadata