Korean pasque-flower
Pulsatilla koreana
Pulsatilla koreana, a plant native to East Asia, has not been traditionally used for any specific medicinal purposes. Scientific research indicates potential benefits in treating atopic dermatitis, as its extract alleviated symptoms and restored skin barrier-related factors in mice studies. Additionally, silver nanoparticles synthesized from Pulsatilla koreana root extract demonstrated significant cytotoxicity against lung cancer cells and potent anti-inflammatory effects by inhibiting the production of nitric oxide (NO) and prostaglandin E2 (PGE2), as well as downregulating iNOS and COX-2 gene expression. The plant also showed promise in bone health, with water extracts suppressing osteoclast differentiation and alleviating bone loss in ovariectomized mice. No major safety issues or known drug interactions have been recorded for Pulsatilla koreana.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- Pk-AuNps de Pulsatilla koreana mostró efectos antiinflamatorios potentes al inhibir la producción de NO y PGE2 y disminuir la expresión génica de iNOS y COX-2 en macrófagos estimulados con LPS.
- Extraídos acuoso de Pulsatilla koreana inhibieron la diferenciación de osteoclastos y aliviaron la pérdida ósea en ratas ovarectomizadas.
- El estudio mostró que las nanopartículas de plata sintetizadas utilizando el extracto de raíz de Pulsatilla koreana demostraron una citotoxicidad significativa contra las células del cáncer de pulmón A549.
- El extracto de Pulsatilla koreana Nakai alivia los síntomas atópicos en ratones y restaura los niveles de factores relacionados con la barrera cutánea, sugiriendo un potencial para tratar la dermatitis atópica.
Frequently asked questions
What is Korean pasque-flower?
Korean pasque-flower (Pulsatilla koreana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Korean pasque-flower?
4 sourced findings are recorded for Korean pasque-flower; the strongest carries evidence grade D. For example: Pk-AuNps de Pulsatilla koreana mostró efectos antiinflamatorios potentes al inhibir la producción de NO y PGE2 y disminuir la expresión génica de iNOS y COX-2 en macrófagos estimulados con LPS.
How strong is the evidence for Korean pasque-flower?
The strongest finding for Korean pasque-flower carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Korean pasque-flower safe? What are the side effects?
No major safety issues are recorded for Korean pasque-flower in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Korean pasque-flower interact with medications?
No drug interactions are recorded for Korean pasque-flower in our sources. This does not rule them out — check with a pharmacist.
Is Korean pasque-flower a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Water Extract of Pulsatilla koreana Nakai Inhibits Osteoclast Differentiation and Alleviates Ovariectomy-Induced Bone Loss. literature abstract metadata
- T2 Pulsatilla koreana Nakai Extract Attenuates Atopic Dermatitis-like Symptoms by Regulating Skin Barrier Factors and Inhibiting the JAK/STAT Pathway. literature abstract metadata
- T2 Modulation of LPS-induced RAW 264.7 macrophages by Pulsatilla koreana-synthesized gold nanoparticles. literature abstract metadata
- T2 Green synthesis, characterization, and anticancer activity of silver nanoparticles via Pulsatilla koreana root extract. literature abstract metadata