Korean pasque-flower
Pulsatilla koreana
紫花杓兰是一种传统药用植物，原产于东亚。尽管其在特定的传统实践中的使用尚未广泛记录，但研究表明它具有多种应用的前景。科学证据表明，紫花杓兰中的化合物，特别是Pk-AuNps，通过抑制一氧化氮（NO）和前列腺素E2（PGE2）的产生以及下调LPS刺激的巨噬细胞中iNOS和COX-2基因表达而表现出强大的抗炎作用。此外，紫花杓兰水提取物被发现可以抑制破骨细胞分化并减轻去卵巢小鼠的骨丢失，这表明其可能对骨骼健康有益。该植物还显示出显著的细胞毒性，当使用其根提取物合成银纳米颗粒时，可针对A549肺癌细胞。此外，紫花杓兰Nakai提取物在小鼠中缓解了过敏症状，通过恢复皮肤屏障相关因子水平表明可能具有治疗特应性皮炎的应用前景。迄今为止，尚未发现该植物存在重大安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自朝鲜银莲花的Pk-AuNps通过抑制NO和PGE2的产生以及下调LPS刺激的巨噬细胞中iNOS和COX-2基因表达，表现出强大的抗炎作用。
- 来自朝鲜风铃草的水提取物抑制了破骨细胞分化并减轻了去卵巢小鼠的骨丢失。
- 研究发现，使用紫草根提取物合成的银纳米颗粒对A549肺癌细胞表现出显著的细胞毒性。
- 来自Nakai的朝鲜风毛菊提取物减轻了小鼠的过敏症状并恢复了与皮肤屏障相关的因子水平，表明其治疗特应性皮炎的潜力。
Frequently asked questions
What is Korean pasque-flower?
Korean pasque-flower (Pulsatilla koreana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Korean pasque-flower?
4 sourced findings are recorded for Korean pasque-flower; the strongest carries evidence grade D. For example: 来自朝鲜银莲花的Pk-AuNps通过抑制NO和PGE2的产生以及下调LPS刺激的巨噬细胞中iNOS和COX-2基因表达，表现出强大的抗炎作用。
How strong is the evidence for Korean pasque-flower?
The strongest finding for Korean pasque-flower carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Korean pasque-flower safe? What are the side effects?
No major safety issues are recorded for Korean pasque-flower in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Korean pasque-flower interact with medications?
No drug interactions are recorded for Korean pasque-flower in our sources. This does not rule them out — check with a pharmacist.
Is Korean pasque-flower a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Water Extract of Pulsatilla koreana Nakai Inhibits Osteoclast Differentiation and Alleviates Ovariectomy-Induced Bone Loss. literature abstract metadata
- T2 Pulsatilla koreana Nakai Extract Attenuates Atopic Dermatitis-like Symptoms by Regulating Skin Barrier Factors and Inhibiting the JAK/STAT Pathway. literature abstract metadata
- T2 Modulation of LPS-induced RAW 264.7 macrophages by Pulsatilla koreana-synthesized gold nanoparticles. literature abstract metadata
- T2 Green synthesis, characterization, and anticancer activity of silver nanoparticles via Pulsatilla koreana root extract. literature abstract metadata