Épurge
Euphorbia lathyris · Caper Spurge
Euphorbia lathyris, commonly known as Mexican tobacco or yellow oleander, is a plant traditionally used in some folk remedies but lacks substantial documented traditional uses. Scientific evidence suggests that Euphorbia lathyris has potential therapeutic applications; salicylic acid treatment enhances diterpenoid production in suspension cultures of the plant. Additionally, ingenol ameliorates silicosis by inhibiting the PTGS2/PI3K/AKT signaling pathway both in vivo and in vitro. Network pharmacology and molecular docking analyses indicate that Euphorbia lathyris seeds may interact with multiple targets involved in cancer-related pathways, potentially treating colorectal cancer. Extracts containing L1 and L3 increase ER stress markers and inhibit cell proliferation in pancreatic cancer cells. To date, no major safety issues or reported drug interactions have been recorded for this plant.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Salicylic acid treatment significantly enhances the production of diterpenoids in Euphorbia lathyris suspension cultures.
- L'ingenol améliore la silicose en inhibant le chemin de signalisation PTGS2/PI3K/AKT tant in vivo que in vitro.
- Une analyse par pharmacologie informatique et de docking moléculaire suggère que la graine d'Euphorbe Lathyrus pourrait interagir avec plusieurs cibles impliquées dans le cancer colorectal via diverses voies.
- Les diterpènes Euphorbia lathyris L1 et L3 augmentent les marqueurs du stress endoplasmaque réticulaire et inhibent la prolifération cellulaire dans les cellules du cancer pancréatique.
Frequently asked questions
What is Épurge?
Épurge (Euphorbia lathyris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Épurge?
4 sourced findings are recorded for Épurge; the strongest carries evidence grade D. For example: Salicylic acid treatment significantly enhances the production of diterpenoids in Euphorbia lathyris suspension cultures.
How strong is the evidence for Épurge?
The strongest finding for Épurge carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Épurge safe? What are the side effects?
No major safety issues are recorded for Épurge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Épurge interact with medications?
No drug interactions are recorded for Épurge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Épurge?
Épurge is also known as: Caper Spurge, Молочай чины.
Is Épurge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Ingenol ameliorates silicosis via targeting the PTGS2/PI3K/AKT signaling axis: Implications for therapeutic intervention. literature abstract metadata
- T2 Inhibition of Cell Proliferation by Euphorbia Factors L1 and L3 from Euphorbia lathyris through the ATF4-CHOP. literature abstract metadata
- T2 Network pharmacology and molecular docking analysis on mechanisms of Euphorbia Lathyris L. seed in treating colorectal cancer. literature abstract metadata
- T2 Salicylic acid-mediated biosynthesis of anti-oomycete diterpenoids in Euphorbia lathyris L. suspension cells. literature abstract metadata