Caper Spurge
Euphorbia lathyris
Euphorbia lathyris, commonly known as Mexican tobacco or yellow oleander, is a plant traditionally used in some folk remedies but lacks substantial documented traditional uses. Scientific evidence suggests that Euphorbia lathyris has potential therapeutic applications; salicylic acid treatment enhances diterpenoid production in suspension cultures of the plant. Additionally, ingenol ameliorates silicosis by inhibiting the PTGS2/PI3K/AKT signaling pathway both in vivo and in vitro. Network pharmacology and molecular docking analyses indicate that Euphorbia lathyris seeds may interact with multiple targets involved in cancer-related pathways, potentially treating colorectal cancer. Extracts containing L1 and L3 increase ER stress markers and inhibit cell proliferation in pancreatic cancer cells. To date, no major safety issues or reported drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Salicylic acid treatment significantly enhances the production of diterpenoids in Euphorbia lathyris suspension cultures.
- Ingenol ameliorates silicosis by inhibiting the PTGS2/PI3K/AKT signaling pathway in both in vivo and in vitro models.
- A network pharmacology and molecular docking analysis suggested that Euphorbia Lathyris seed may interact with multiple targets involved in colorectal cancer through various pathways.
- Euphorbia lathyris diterpenoids L1 and L3 increased ER stress markers and inhibited cell proliferation in pancreatic cancer cells.
Frequently asked questions
What is Caper Spurge?
Caper Spurge (Euphorbia lathyris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Caper Spurge?
4 sourced findings are recorded for Caper Spurge; the strongest carries evidence grade D. For example: Salicylic acid treatment significantly enhances the production of diterpenoids in Euphorbia lathyris suspension cultures.
How strong is the evidence for Caper Spurge?
The strongest finding for Caper Spurge carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Caper Spurge safe? What are the side effects?
No major safety issues are recorded for Caper Spurge in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Caper Spurge interact with medications?
No drug interactions are recorded for Caper Spurge in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Caper Spurge?
Caper Spurge is also known as: Молочай чины, Épurge.
Is Caper Spurge a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Ingenol ameliorates silicosis via targeting the PTGS2/PI3K/AKT signaling axis: Implications for therapeutic intervention. literature abstract metadata
- T2 Inhibition of Cell Proliferation by Euphorbia Factors L1 and L3 from Euphorbia lathyris through the ATF4-CHOP. literature abstract metadata
- T2 Network pharmacology and molecular docking analysis on mechanisms of Euphorbia Lathyris L. seed in treating colorectal cancer. literature abstract metadata
- T2 Salicylic acid-mediated biosynthesis of anti-oomycete diterpenoids in Euphorbia lathyris L. suspension cells. literature abstract metadata