Lobélie
Lobelia · Giant Lobelia
Lobelia is a plant traditionally associated with Native American medicine, particularly among tribes in North America. It has been used for various purposes such as treating respiratory conditions and as an emetic. However, there are no well-documented traditional uses outside of this context. Scientific evidence regarding lobelia's efficacy is limited. A study found that even low concentrations of sucralose affected the gas exchange, chlorophyll content, and flowering hue in three North American prairie species, though these findings do not directly relate to human use. Another study identified antitrypanosomal activity for lobetyolin from Lobelia rhynchopetalum, both in vitro and in vivo against Trypanosoma congolense; however, further validation is needed before drawing strong conclusions. Safety concerns are minimal based on current data, with no major issues recorded. There are also no reported drug interactions associated with lobelia.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait de Lobelia chinensis réprime la différenciation des ostéoclastes par l'inhibition double des voies JNK/nF-κB et btk/PLCγ2, potentiellement en faisant d'elle un agent antirésorbption pour l'ostéoporose.
- L'étude a montré que le lobétiole provenant de Lobelia rhynchopetalum présente une activité antitrypanosomale tant in vitro qu'in vivo contre Trypanosoma congolense, bien que des validations supplémentaires soient nécessaires.
- Les diètes des espèces de sauterelles alpines syntropiques comprenaient un large éventail de plantes, avec des buissons et des herbes comme Gaultheria et Lobelia étant préférées.
- L'étude a identifié 137 métabolites à faible poids moléculaire chez 11 espèces macrophytes, avec les acides gras étant un composant commun.
- Même des concentrations faibles de sucralose ont affecté l'échange gazeux, le contenu en chlorophylle et la teinte du floraison chez trois espèces de prairie nord-américaines.
Frequently asked questions
What is Lobélie?
Lobélie (Lobelia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lobélie?
5 sourced findings are recorded for Lobélie; the strongest carries evidence grade D. For example: L'extrait de Lobelia chinensis réprime la différenciation des ostéoclastes par l'inhibition double des voies JNK/nF-κB et btk/PLCγ2, potentiellement en faisant d'elle un agent antirésorbption pour l'ostéoporose.
How strong is the evidence for Lobélie?
The strongest finding for Lobélie carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lobélie safe? What are the side effects?
No major safety issues are recorded for Lobélie in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lobélie interact with medications?
No drug interactions are recorded for Lobélie in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lobélie?
Lobélie is also known as: Giant Lobelia, лобелия.
Is Lobélie a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From Lobelia rhynchopetalum Hemsl. Root Extract Against Trypanosoma congolense Field Isolates. literature abstract metadata
- T2 Major Low-Molecular-Weight Metabolites from Freshwater Aquatic Macrophytes: Ecological Aspects. literature abstract metadata
- T2 Dietary Overlap of Sympatric Polyphagous Alpine Grasshoppers Includes Invasive Plant Species. literature abstract metadata
- T2 Environmentally-relevant concentrations of dissolved sucralose affect gas exchange, chlorophyll content, and flowering hue of three North American prairie species. literature abstract metadata
- T2 Lobelia chinensis extract suppresses osteoclast differentiation through dual inhibition of JNK/nF-κB and btk/PLCγ2 pathways. literature abstract metadata