Giant Lobelia
Lobelia
Lobelia is a plant traditionally associated with Native American medicine, particularly among tribes in North America. It has been used for various purposes such as treating respiratory conditions and as an emetic. However, there are no well-documented traditional uses outside of this context. Scientific evidence regarding lobelia's efficacy is limited. A study found that even low concentrations of sucralose affected the gas exchange, chlorophyll content, and flowering hue in three North American prairie species, though these findings do not directly relate to human use. Another study identified antitrypanosomal activity for lobetyolin from Lobelia rhynchopetalum, both in vitro and in vivo against Trypanosoma congolense; however, further validation is needed before drawing strong conclusions. Safety concerns are minimal based on current data, with no major issues recorded. There are also no reported drug interactions associated with lobelia.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Lobelia chinensis extract suppresses osteoclast differentiation through dual inhibition of JNK/nF-κB and btk/PLCγ2 pathways, potentially making it an anti-resorptive agent for osteoporosis.
- The study found that lobetyolin from Lobelia rhynchopetalum exhibits antitrypanosomal activity both in vitro and in vivo against Trypanosoma congolense, though further validation is needed.
- The diets of sympatric alpine grasshopper species included a wide range of plants, with shrubs and herbs like Gaultheria and Lobelia being favored.
- The study identified 137 major low-molecular-weight metabolites in 11 macrophyte species, with fatty acids being a common component.
- Even low concentrations of sucralose affected gas exchange, chlorophyll content, and flowering hue in three North American prairie species.
Frequently asked questions
What is Giant Lobelia?
Giant Lobelia (Lobelia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Giant Lobelia?
5 sourced findings are recorded for Giant Lobelia; the strongest carries evidence grade D. For example: Lobelia chinensis extract suppresses osteoclast differentiation through dual inhibition of JNK/nF-κB and btk/PLCγ2 pathways, potentially making it an anti-resorptive agent for osteoporosis.
How strong is the evidence for Giant Lobelia?
The strongest finding for Giant Lobelia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Giant Lobelia safe? What are the side effects?
No major safety issues are recorded for Giant Lobelia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Giant Lobelia interact with medications?
No drug interactions are recorded for Giant Lobelia in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Giant Lobelia?
Giant Lobelia is also known as: лобелия, Lobélie.
Is Giant Lobelia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From Lobelia rhynchopetalum Hemsl. Root Extract Against Trypanosoma congolense Field Isolates. literature abstract metadata
- T2 Major Low-Molecular-Weight Metabolites from Freshwater Aquatic Macrophytes: Ecological Aspects. literature abstract metadata
- T2 Dietary Overlap of Sympatric Polyphagous Alpine Grasshoppers Includes Invasive Plant Species. literature abstract metadata
- T2 Environmentally-relevant concentrations of dissolved sucralose affect gas exchange, chlorophyll content, and flowering hue of three North American prairie species. literature abstract metadata
- T2 Lobelia chinensis extract suppresses osteoclast differentiation through dual inhibition of JNK/nF-κB and btk/PLCγ2 pathways. literature abstract metadata