Pædérie fétide
Paederia foetida · Chinese fever vine
Paederia foetida is a plant traditionally used in Ayurvedic and folk medicine practices. It has been utilized for various ailments, though specific traditional uses are not well-documented. Scientific studies have identified four compounds with potential antibacterial properties against Staphylococcus aureus peptide deformylase; however, further experimental validation is required to confirm these findings. The plant's leaf extract demonstrated dose-dependent hematological and hepatic effects in rats at higher doses, indicating possible toxicity concerns. Paederia foetida also showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity, suggesting potential benefits for liver health. Two new iridoid glycosides were identified from the plant, one of which exhibited potential hepatoprotective activity. No major safety issues or drug interactions have been recorded to date, but further research is necessary to fully understand its effects and applications.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait hydro-alcoolique de Paederia foetida a montré des effets protecteurs hépatiques significatifs chez les souris avec une toxicité hépataque induite par CCl₄.
- Deux nouveaux glycosides iridoylés ont été identifiés chez Paederia foetida, avec l'un d'eux montrant une activité protectrice hépatique potentielle.
- L'étude a identifié quatre composés issus de Paederia foetida avec le potentiel d'inhiber la déformylase de péptides de Staphylococcus aureus, bien que des validations expérimentales soient nécessaires.
- Une exposition aiguë à l'extrait de feuille de Paederia foetida a provoqué des réponses hémato-lobardes et hépatiques dose-dépendantes à plus haute dose chez les rats Wistar.
Frequently asked questions
What is Pædérie fétide?
Pædérie fétide (Paederia foetida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pædérie fétide?
4 sourced findings are recorded for Pædérie fétide; the strongest carries evidence grade D. For example: L'extrait hydro-alcoolique de Paederia foetida a montré des effets protecteurs hépatiques significatifs chez les souris avec une toxicité hépataque induite par CCl₄.
How strong is the evidence for Pædérie fétide?
The strongest finding for Pædérie fétide carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pædérie fétide safe? What are the side effects?
No major safety issues are recorded for Pædérie fétide in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pædérie fétide interact with medications?
No drug interactions are recorded for Pædérie fétide in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Pædérie fétide?
Pædérie fétide is also known as: Chinese fever vine.
Is Pædérie fétide a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Hepatoprotective iridoid glycosides from the aerial parts of Paederia foetida. literature abstract metadata
- T2 Acute oral toxicity and hepatic responses to Paederia foetida leaf extract in Wistar rats. literature abstract metadata
- T2 Assessment of the Hepatoprotective and Antioxidant Properties of Hydroalcoholic Extract of Paederia foetida. literature abstract metadata
- T2 Computational Identification of Paederia foetida Linn. Phytochemicals as Potential Inhibitors of Staphylococcus aureus Peptide Deformylase. literature abstract metadata