Chinese fever vine
Paederia foetida
Paederia foetida is a plant traditionally used in Ayurvedic and folk medicine practices. It has been utilized for various ailments, though specific traditional uses are not well-documented. Scientific studies have identified four compounds with potential antibacterial properties against Staphylococcus aureus peptide deformylase; however, further experimental validation is required to confirm these findings. The plant's leaf extract demonstrated dose-dependent hematological and hepatic effects in rats at higher doses, indicating possible toxicity concerns. Paederia foetida also showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity, suggesting potential benefits for liver health. Two new iridoid glycosides were identified from the plant, one of which exhibited potential hepatoprotective activity. No major safety issues or drug interactions have been recorded to date, but further research is necessary to fully understand its effects and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Paederia foetida's hydroalcoholic extract showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity.
- Two new iridoid glycosides were identified from Paederia foetida, with one showing potential hepatoprotective activity.
- The study identified four compounds from Paederia foetida with potential to inhibit Staphylococcus aureus peptide deformylase, though experimental validation is needed.
- Acute exposure to Paederia foetida leaf extract induced dose-associated hematological and hepatic responses at higher doses in Wistar rats.
Frequently asked questions
What is Chinese fever vine?
Chinese fever vine (Paederia foetida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese fever vine?
4 sourced findings are recorded for Chinese fever vine; the strongest carries evidence grade D. For example: Paederia foetida's hydroalcoholic extract showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity.
How strong is the evidence for Chinese fever vine?
The strongest finding for Chinese fever vine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese fever vine safe? What are the side effects?
No major safety issues are recorded for Chinese fever vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese fever vine interact with medications?
No drug interactions are recorded for Chinese fever vine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese fever vine?
Chinese fever vine is also known as: Pædérie fétide.
Is Chinese fever vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Hepatoprotective iridoid glycosides from the aerial parts of Paederia foetida. literature abstract metadata
- T2 Acute oral toxicity and hepatic responses to Paederia foetida leaf extract in Wistar rats. literature abstract metadata
- T2 Assessment of the Hepatoprotective and Antioxidant Properties of Hydroalcoholic Extract of Paederia foetida. literature abstract metadata
- T2 Computational Identification of Paederia foetida Linn. Phytochemicals as Potential Inhibitors of Staphylococcus aureus Peptide Deformylase. literature abstract metadata