Chinese fever vine
Paederia foetida
Paederia foetida, commonly known as "stinking shrub," is a traditional plant used in Ayurvedic and folk medicine practices. While its specific uses vary across different traditions, it has not been extensively documented for any particular medical applications. Scientific studies have shown promising results with Paederia foetida's hydroalcoholic extract exhibiting significant hepatoprotective effects in mice with CCl₄-induced liver toxicity. Additionally, two new iridoid glycosides were identified from the plant, one of which showed potential hepatoprotective activity. Four compounds from the plant demonstrated potential to inhibit Staphylococcus aureus peptide deformylase; however, further experimental validation is needed for these findings. Acute exposure to Paederia foetida leaf extract induced dose-associated hematological and hepatic responses at higher doses in Wistar rats, suggesting that caution should be exercised with high dosages. No major safety issues or recorded drug interactions have been reported thus far.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Paederia foetida's hydroalcoholic extract showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity.
- Two new iridoid glycosides were identified from Paederia foetida, with one showing potential hepatoprotective activity.
- The study identified four compounds from Paederia foetida with potential to inhibit Staphylococcus aureus peptide deformylase, though experimental validation is needed.
- Acute exposure to Paederia foetida leaf extract induced dose-associated hematological and hepatic responses at higher doses in Wistar rats.
Frequently asked questions
What is Chinese fever vine?
Chinese fever vine (Paederia foetida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese fever vine?
4 sourced findings are recorded for Chinese fever vine; the strongest carries evidence grade D. For example: Paederia foetida's hydroalcoholic extract showed significant hepatoprotective effects in mice with CCl₄-induced liver toxicity.
How strong is the evidence for Chinese fever vine?
The strongest finding for Chinese fever vine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese fever vine safe? What are the side effects?
No major safety issues are recorded for Chinese fever vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese fever vine interact with medications?
No drug interactions are recorded for Chinese fever vine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese fever vine?
Chinese fever vine is also known as: Pædérie fétide.
Is Chinese fever vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Hepatoprotective iridoid glycosides from the aerial parts of Paederia foetida. literature abstract metadata
- T2 Acute oral toxicity and hepatic responses to Paederia foetida leaf extract in Wistar rats. literature abstract metadata
- T2 Assessment of the Hepatoprotective and Antioxidant Properties of Hydroalcoholic Extract of Paederia foetida. literature abstract metadata
- T2 Computational Identification of Paederia foetida Linn. Phytochemicals as Potential Inhibitors of Staphylococcus aureus Peptide Deformylase. literature abstract metadata