cubèbe
Piper cubeba · Cubeb
Piper cubeba, also known as cubeb or javel pepper, is a traditional medicine plant native to Southeast Asia. Traditionally, it has not been extensively used in any specific medical practices. Scientific evidence suggests that extracts from Piper cubeba exhibit significant inhibitory activity against E. coli O157:H7 and have shown promise in inducing apoptosis in breast cancer cells through reactive oxygen species-mediated mitochondrial dysfunction. Additionally, a study found that a cubebinol-CuO nanocomposite derived from the seeds of this plant could be useful for both tetracycline sensing and degradation. In an animal model, irradiated P. cubeba reduced inflammation and oxidative stress markers in rats with CFA-induced arthritis by increasing IL-10 and FOXP3 expression. To date, no major safety concerns or reported drug interactions have been recorded regarding Piper cubeba.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait de Piper cubeba a montré une activité inhibitrice significative contre E. coli O157:H7 in vitro.
- Le hinokinin issu de Piper cubeba a provoqué l'apoptose des cellules cancéreuses du sein MCF-7 par voie d'une dysfonction mitochondriale via les espèces réactives d'oxygène.
- L'étude a montré que le nanocomposant de cubebinol-CuO des graines de Piper cubeba affiche des capacités prometteuses pour la détection et la dégradation de la tétracycline.
- Le P. cubeba irradié a réduit l'inflammation et les marqueurs d'stress oxydatif tout en augmentant les niveaux d'IL-10 chez les rats à l'arthrite induite par CFA.
Frequently asked questions
What is cubèbe?
cubèbe (Piper cubeba) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about cubèbe?
4 sourced findings are recorded for cubèbe; the strongest carries evidence grade D. For example: L'extrait de Piper cubeba a montré une activité inhibitrice significative contre E. coli O157:H7 in vitro.
How strong is the evidence for cubèbe?
The strongest finding for cubèbe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is cubèbe safe? What are the side effects?
No major safety issues are recorded for cubèbe in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does cubèbe interact with medications?
No drug interactions are recorded for cubèbe in our sources. This does not rule them out — check with a pharmacist.
What are the common names of cubèbe?
cubèbe is also known as: Cubeb, Перец кубеба.
Is cubèbe a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A smart cubebinol-CuO nanocomposite for dual electrochemical sensing and visible-light-driven photodegradation of tetracycline: Box-Behnken optimization, mechanistic insight and kinetics. literature abstract metadata
- T2 Hinokinin, a lignan from Piper cubeba fruits induces apoptosis via reactive oxygen species-mediated mitochondrial dysfunction in MCF-7 breast cancer cells. literature abstract metadata
- T2 Escherichia coli O157:H7 prevalence in Upper Egypt: impacts on food safety and human Health, with a protection trial using natural antibacterial Piper cubeba. literature abstract metadata
- T2 Immunomodulatory and Antioxidant Potencies of γ-irradiated Piper cubeba in Complete Freund's Adjuvant-Induced Arthritis in Rats. literature abstract metadata