Cubeb
Piper cubeba
Piper cubeba, also known as cubeb or javel pepper, is a traditional medicine plant native to Southeast Asia. Traditionally, it has not been extensively used in any specific medical practices. Scientific evidence suggests that extracts from Piper cubeba exhibit significant inhibitory activity against E. coli O157:H7 and have shown promise in inducing apoptosis in breast cancer cells through reactive oxygen species-mediated mitochondrial dysfunction. Additionally, a study found that a cubebinol-CuO nanocomposite derived from the seeds of this plant could be useful for both tetracycline sensing and degradation. In an animal model, irradiated P. cubeba reduced inflammation and oxidative stress markers in rats with CFA-induced arthritis by increasing IL-10 and FOXP3 expression. To date, no major safety concerns or reported drug interactions have been recorded regarding Piper cubeba.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。
科学怎么说
- 胡椒提取物在体外对O157:H7大肠杆菌显示出显著的抑制活性。
- 来自胡椒树皮(Piper cubeba)的 hinokinin 在反应性氧物种介导的线粒体功能障碍途径中诱导了 MCF-7 乳腺癌细胞凋亡。
- 研究发现,来自胡椒树子的立方烯醇-CuO纳米复合材料显示出有希望的双功能特性,可用于四环素的检测和降解。
- 辐照P. cubeba 减少了炎症和氧化应激标志物,同时增加了CFA诱导的关节炎大鼠的IL-10水平。
Frequently asked questions
What is Cubeb?
Cubeb (Piper cubeba) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cubeb?
4 sourced findings are recorded for Cubeb; the strongest carries evidence grade D. For example: 胡椒提取物在体外对O157:H7大肠杆菌显示出显著的抑制活性。
How strong is the evidence for Cubeb?
The strongest finding for Cubeb carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cubeb safe? What are the side effects?
No major safety issues are recorded for Cubeb in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cubeb interact with medications?
No drug interactions are recorded for Cubeb in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cubeb?
Cubeb is also known as: Перец кубеба, cubèbe.
Is Cubeb a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 A smart cubebinol-CuO nanocomposite for dual electrochemical sensing and visible-light-driven photodegradation of tetracycline: Box-Behnken optimization, mechanistic insight and kinetics. literature abstract metadata
- T2 Hinokinin, a lignan from Piper cubeba fruits induces apoptosis via reactive oxygen species-mediated mitochondrial dysfunction in MCF-7 breast cancer cells. literature abstract metadata
- T2 Escherichia coli O157:H7 prevalence in Upper Egypt: impacts on food safety and human Health, with a protection trial using natural antibacterial Piper cubeba. literature abstract metadata
- T2 Immunomodulatory and Antioxidant Potencies of γ-irradiated Piper cubeba in Complete Freund's Adjuvant-Induced Arthritis in Rats. literature abstract metadata