Swertie
Swertia · Felwort
Swertia is a plant traditionally associated with the Himalayan region. While its specific traditional uses are not well-documented, it has been studied for various potential health benefits. Scientific research indicates that Swertia mussotii contains novel compounds such as swertimusins A‒D, which show some anti-inflammatory activity. Additionally, erythrocentaurin from this plant was found to significantly inhibit hepatitis B virus (HBV) replication and reverse 55 metabolites in models, while also suppressing the NF-κB pathway both in vivo and in vitro. Phylogenetic studies using rbcL and trnH-psbA markers have provided reliable species identification for endemic Himalayan plant species, including Swertia mussotii. In a study involving non-alcoholic fatty liver disease (NAFLD) rats, treatment with Swertia mussotii reduced body weight, serum lipids, hepatic lipid accumulation, liver inflammation, and oxidative stress, while also restoring metabolic pathways. No major safety issues or recorded drug interactions have been identified to date.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Quatre paires de composés nouveaux, les swertimusines A‒D, ont été identifiées chez Swertia mussotii, montrant une activité anti-inflammatoire certaine.
- L'erythrocentaurin a inhibi de manière significative la réplication du HBV, a rétabli 55 métabolites et a supprimé le cheminée de la voie NF-κB dans les modèles both in vivo et in vitro.
- L'étude a montré que les marqueurs rbcL et trnH-psbA ont fourni une identification des espèces fiable et une résolution phylogénétique pour les espèces endémiques dans les Himalayes occidentaux.
- Swertia mussotii treatment reduced body weight, lipid levels, liver inflammation, and oxidative stress, and restored metabolic pathways while activating SIRT1/AMPK in NAFLD rats.
Frequently asked questions
What is Swertie?
Swertie (Swertia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Swertie?
4 sourced findings are recorded for Swertie; the strongest carries evidence grade D. For example: Quatre paires de composés nouveaux, les swertimusines A‒D, ont été identifiées chez Swertia mussotii, montrant une activité anti-inflammatoire certaine.
How strong is the evidence for Swertie?
The strongest finding for Swertie carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Swertie safe? What are the side effects?
No major safety issues are recorded for Swertie in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Swertie interact with medications?
No drug interactions are recorded for Swertie in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Swertie?
Swertie is also known as: Felwort, сверция.
Is Swertie a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS. literature abstract metadata
- T2 Untargeted Metabolomic Analysis Reveals the Mechanism Underlying Swertia mussotii Treatment on Rats With Non-Alcoholic Fatty Liver Disease Using UPLC-Q-TOF/MS. literature abstract metadata
- T2 Discovery of swertimusins A‒D: Four pairs of rearranged nor-secoiridoid derivatives with a hexahydrofuro[2,3-b]furan ring from Swertia mussotii. literature abstract metadata
- T2 DNA barcoding and phylogenetic insights into the selected endemic flora of the Western Himalayas. literature abstract metadata