Felwort
Swertia
Swertia is a plant traditionally associated with the western Himalayan region. While specific traditional uses for Swertia are not well-documented, it has shown promise in scientific research. Studies have identified four novel compounds, swertimusins A‒D, from Swertia mussotii that exhibit some anti-inflammatory activity. Additionally, erythrocentaurin demonstrated significant inhibition of hepatitis B virus replication and modulation of metabolic pathways in both in vivo and in vitro models. Phylogenetic analysis using rbcL and trnH-psbA markers provided reliable species identification for endemic plant species in the western Himalayas. In a study on non-alcoholic fatty liver disease (NAFLD), Swertia mussotii treatment reduced body weight, lipid levels, liver inflammation, and oxidative stress while activating SIRT1/AMPK pathways. Safety data indicates no major issues have been recorded for Swertia. There are currently no reported drug interactions associated with its use.
- Traditionally for
- fever · medicinal
- Traditions
- Ayurveda · traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- fever
- medicinal
What the science says
- Four pairs of novel compounds, swertimusins A‒D, were identified from Swertia mussotii, showing some anti-inflammatory activity.
- Erythrocentaurin significantly inhibited HBV replication, reversed 55 metabolites, and suppressed the NF-κB pathway in both in vivo and in vitro models.
- The study found that rbcL and trnH-psbA markers provided reliable species identification and phylogenetic resolution for endemic plant species in the western Himalayas.
- Swertia mussotii treatment reduced body weight, lipid levels, liver inflammation, and oxidative stress, and restored metabolic pathways while activating SIRT1/AMPK in NAFLD rats.
Frequently asked questions
What is Felwort?
Felwort (Swertia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Felwort traditionally used for?
Traditional sources record Felwort for: fever, medicinal. This reflects traditional use, not a proven medical treatment.
Which traditions use Felwort?
Felwort appears in these traditions in our sources: Ayurveda, traditional.
What does the scientific evidence say about Felwort?
4 sourced findings are recorded for Felwort; the strongest carries evidence grade D. For example: Four pairs of novel compounds, swertimusins A‒D, were identified from Swertia mussotii, showing some anti-inflammatory activity.
How strong is the evidence for Felwort?
The strongest finding for Felwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Felwort safe? What are the side effects?
No major safety issues are recorded for Felwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Felwort interact with medications?
No drug interactions are recorded for Felwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Felwort?
Felwort is also known as: сверция, Swertie.
Is Felwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS. literature abstract metadata
- T2 Untargeted Metabolomic Analysis Reveals the Mechanism Underlying Swertia mussotii Treatment on Rats With Non-Alcoholic Fatty Liver Disease Using UPLC-Q-TOF/MS. literature abstract metadata
- T2 Discovery of swertimusins A‒D: Four pairs of rearranged nor-secoiridoid derivatives with a hexahydrofuro[2,3-b]furan ring from Swertia mussotii. literature abstract metadata
- T2 DNA barcoding and phylogenetic insights into the selected endemic flora of the Western Himalayas. literature abstract metadata
- T3 Swertia CC BY-SA 4.0