Abuta grandifolia

Abuta grandifolia, a plant native to Central America, has not been extensively documented in traditional medicine. Scientific studies have primarily focused on its biological properties rather than therapeutic uses. Research indicates that various parts of the plant, including fruit, leaves, and seeds, are commonly consumed. There is preliminary evidence suggesting potential renoprotective effects from Abuta grandifolia, which could help prevent kidney function reductions due to ischemia. Additionally, krukovine, a compound derived from this plant, has shown antiproliferative activity in oxaliplatin-resistant pancreatic cancer cells and organoids, with enhanced efficacy when combined with oxaliplatin. It also inhibits the growth and proliferation of KRAS-mutated lung cancer cells by downregulating RAF-ERK and AKT pathways. No major safety concerns or recorded drug interactions have been identified to date.

केवल जानकारी हेतु। पारंपरिक उपयोग का अर्थ सिद्ध प्रभावशीलता नहीं है। प्रमाण और सुरक्षा भिन्न होती है — उद्धृत स्रोत देखें।