FolkKB

Abuta grandifolia

Abuta grandifolia

Abuta grandifolia 是一种在传统医学实践中未广泛记录的植物。科学证据表明其可能具有肾保护作用，这可能有助于预防因缺血而导致的一些肾功能减退。此外，来自 Abuta grandifolia 的 krukovine 在 KRAS 突变型肺癌细胞和对奥沙利铂耐药的胰腺癌细胞中显示出抗增殖效应，并且与奥沙利铂联合使用时抑制作用增强。然而，目前没有记录到与其相关的重大安全问题或药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 审查发现水果、叶片和种子的消费占主导地位，占总使用部分的85.8%。 A PMID
  • 研究表明Abuta grandifolia可能促进肾保护，防止由于缺血引起的一些肾功能减退。 D PMID
  • 来自阿布塔·格兰迪folia的膏剂通过下调RAF-ERK和AKT途径抑制KRAS突变肺癌细胞的生长和增殖。 D PMID
  • KV 在抗奥沙利铂胰腺癌细胞和类器官中表现出抑制增殖作用，并与奥沙利铂联合使用时抑制作用增强。 D PMID

Frequently asked questions

What is Abuta grandifolia?

Abuta grandifolia (Abuta grandifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Abuta grandifolia?

4 sourced findings are recorded for Abuta grandifolia; the strongest carries evidence grade A. For example: 审查发现水果、叶片和种子的消费占主导地位，占总使用部分的85.8%。

How strong is the evidence for Abuta grandifolia?

The strongest finding for Abuta grandifolia carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Abuta grandifolia safe? What are the side effects?

No major safety issues are recorded for Abuta grandifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Abuta grandifolia interact with medications?

No drug interactions are recorded for Abuta grandifolia in our sources. This does not rule them out — check with a pharmacist.

Is Abuta grandifolia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Krukovine Suppresses KRAS-Mutated Lung Cancer Cell Growth and Proliferation by Inhibiting the RAF-ERK Pathway and Inactivating AKT Pathway. literature abstract metadata
  2. T2 Antiproliferative Activity of Krukovine by Regulating Transmembrane Protein 139 (TMEM139) in Oxaliplatin-Resistant Pancreatic Cancer Cells. literature abstract metadata
  3. T2 Amazonia Phytotherapy Reduces Ischemia and Reperfusion Injury in the Kidneys. literature abstract metadata
  4. T2 Patterns of use of wild food plants by Brazilian local communities: systematic review and meta-analysis. literature abstract metadata

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