Autumn Monkshood
Aconitum carmichaelii
Aconitum carmichaelii，通常称为附子或中国黑狼毒，是一种传统植物，在东亚医学中被使用。它因其对心脏和肌肉系统的潜在效果而被传统上使用，但具体用途尚未得到充分记录。科学数据表明，Aconitum carmichaelii 的主根（CHW）和侧根（FZ）含有 12 种二萜类生物碱，这可能会影响这些部分之间的抗炎活性差异。然而，关于 SFI（附子的加工形式）的临床益处目前证据有限，因为它们证实了未充分加工的附子可能会带来严重的心脏毒性和神经毒性风险。由 Aconitum carmichaelii 提取的 Qishen 膏剂在心肌细胞中通过上调 Cx43 在驻留巨噬细胞中的表达显示出改善心传导和功能的潜力，但临床证据有限。对于这种植物没有记录到主要的安全问题或药物相互作用，尽管其使用应谨慎对待，因为与不适当加工相关的历史风险有关。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究确定了12个二萜生物碱标记物，与主要根（CHW）和侧根（FZ）中黄连的抗炎活性差异有关。
- 当前证据证实，未经充分处理的附子会带来严重的心脏毒性和神经毒性风险。
- SFI 可能通过多种机制对由败血症引起的急性胃肠道损伤产生保护作用，但目前的临床证据有限。
- Qishen膏通过上调心肌驻留巨噬细胞中的Cx43改善了心力衰竭小鼠的心脏传导和功能。
- 单次预防性给予复方丹参（SFD）在寒冷海水暴露前显著延长了大鼠存活时间，与UCP1上调和增强的产热作用相关。
Frequently asked questions
What is Autumn Monkshood?
Autumn Monkshood (Aconitum carmichaelii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Autumn Monkshood?
5 sourced findings are recorded for Autumn Monkshood; the strongest carries evidence grade D. For example: 研究确定了12个二萜生物碱标记物，与主要根（CHW）和侧根（FZ）中黄连的抗炎活性差异有关。
How strong is the evidence for Autumn Monkshood?
The strongest finding for Autumn Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Autumn Monkshood safe? What are the side effects?
No major safety issues are recorded for Autumn Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Autumn Monkshood interact with medications?
No drug interactions are recorded for Autumn Monkshood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Autumn Monkshood?
Autumn Monkshood is also known as: Борец Кармихеля, Aconit de Carmichael.
Is Autumn Monkshood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Shenfu injection in sepsis-induced acute gastrointestinal injury: a narrative review of mechanisms and current evidence. literature abstract metadata
- T2 Toxicology and detoxification processing of Fuzi (Aconitum carmichaelii Debeaux lateral root): a comprehensive review integrating historical perspectives and modern research. literature abstract metadata
- T2 Bioactive Constituents and Therapeutic Mechanisms of Shenfu Decoction in a Rat Model of Seawater-Immersion-Induced Accidental Hypothermia. literature abstract metadata
- T2 Novel insights into anti-inflammatory activity-related metabolic markers and biosynthetic regulatory mechanisms between principal and lateral roots of Aconitum carmichaelii Debx. via integrated metabolomics and transcriptomics. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata