Autumn Monkshood

Aconitum carmichaelii

Aconitum carmichaelii,通常被称为Fuzi或中国乌头根,在东亚医学中,特别是在中国,被用作传统植物。它因其被认为具有温热和镇痛作用而被传统上使用;然而,具体的用途可能因不同的传统而异,并没有明确的共识来确定其应用方式。科学证据表明,该根的主要成分包括12种二萜生物碱,这些生物碱显示出抗炎活性的潜力;但是,主要根(CHW)和侧根(FZ)之间存在差异。然而,未经处理的Fuzi因其强烈的毒性而被广泛认为具有显著的心脏毒性和神经毒性风险。一些研究表明,经过加工的Aconitum carmichaelii形式SFI可能通过多种机制对由败血症引起的急性胃肠道损伤具有保护作用,尽管临床证据有限。从这种植物中提取的Qishen膏剂在心力衰竭小鼠中显示出改善心脏传导和功能的潜力,通过上调Cx43在心脏驻留巨噬细胞中的表达。Aconitum carmichaelii没有记录到主要的安全问题或药物相互作用;然而,由于其毒性,它应该谨慎处理并在专业监督下进行。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究确定了12个二萜生物碱标记物,与主要根(CHW)和侧根(FZ)中黄连的抗炎活性差异有关。 D PMID
  • 当前证据证实,未经充分处理的附子会带来严重的心脏毒性和神经毒性风险。 D PMID
  • SFI 可能通过多种机制对由败血症引起的急性胃肠道损伤产生保护作用,但目前的临床证据有限。 D PMID
  • Qishen膏通过上调心肌驻留巨噬细胞中的Cx43改善了心力衰竭小鼠的心脏传导和功能。 D PMID
  • 单次预防性给予复方丹参(SFD)在寒冷海水暴露前显著延长了大鼠存活时间,与UCP1上调和增强的产热作用相关。 D PMID

Frequently asked questions

What is Autumn Monkshood?

Autumn Monkshood (Aconitum carmichaelii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Autumn Monkshood?

5 sourced findings are recorded for Autumn Monkshood; the strongest carries evidence grade D. For example: 研究确定了12个二萜生物碱标记物,与主要根(CHW)和侧根(FZ)中黄连的抗炎活性差异有关。

How strong is the evidence for Autumn Monkshood?

The strongest finding for Autumn Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Autumn Monkshood safe? What are the side effects?

No major safety issues are recorded for Autumn Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Autumn Monkshood interact with medications?

No drug interactions are recorded for Autumn Monkshood in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Autumn Monkshood?

Autumn Monkshood is also known as: Борец Кармихеля, Aconit de Carmichael.

Is Autumn Monkshood a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Shenfu injection in sepsis-induced acute gastrointestinal injury: a narrative review of mechanisms and current evidence. literature abstract metadata
  2. T2 Toxicology and detoxification processing of Fuzi (Aconitum carmichaelii Debeaux lateral root): a comprehensive review integrating historical perspectives and modern research. literature abstract metadata
  3. T2 Bioactive Constituents and Therapeutic Mechanisms of Shenfu Decoction in a Rat Model of Seawater-Immersion-Induced Accidental Hypothermia. literature abstract metadata
  4. T2 Novel insights into anti-inflammatory activity-related metabolic markers and biosynthetic regulatory mechanisms between principal and lateral roots of Aconitum carmichaelii Debx. via integrated metabolomics and transcriptomics. literature abstract metadata
  5. T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata