Autumn Monkshood
Aconitum carmichaelii
Aconitum carmichaelii, commonly known as Fuzi or Chinese black wolfsbane, is a traditional plant used in East Asian medicine. It has been traditionally utilized for its purported effects on heart and muscle conditions but specific uses are not well-documented. Scientific evidence suggests that the principal roots (CHW) and lateral roots (FZ) of Aconitum carmichaelii contain 12 diterpenoid alkaloids, which may contribute to anti-inflammatory activity differences between these parts. However, current evidence is limited regarding the clinical benefits of SFI (a processed form of Fuzi), as it confirms that inadequately processed Fuzi can pose severe cardiotoxic and neurotoxic risks. Qishen paste, a formulation derived from Aconitum carmichaelii, has shown potential in improving cardiac conduction and function in heart failure mice by upregulating Cx43 in cardiac resident macrophages, but clinical evidence remains limited. No major safety issues or drug interactions have been recorded for this plant, though its use should be approached with caution due to the historical risks associated with improper processing.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 12 diterpenoid alkaloid markers related to anti-inflammatory activity differences between principal roots (CHW) and lateral roots (FZ) of Aconitum carmichaelii.
- Current evidence confirms that inadequately processed Fuzi poses severe cardiotoxic and neurotoxic risks.
- SFI may exert protective effects on sepsis-induced acute gastrointestinal injury through multiple mechanisms, but current clinical evidence is limited.
- Qishen paste improved cardiac conduction and function in heart failure mice by upregulating Cx43 in cardiac resident macrophages.
- A single prophylactic administration of Shenfu Decoction (SFD) before cold seawater exposure significantly prolongs rat survival time, associated with UCP1 upregulation and enhanced thermogenesis.
Frequently asked questions
What is Autumn Monkshood?
Autumn Monkshood (Aconitum carmichaelii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Autumn Monkshood?
5 sourced findings are recorded for Autumn Monkshood; the strongest carries evidence grade D. For example: The study identified 12 diterpenoid alkaloid markers related to anti-inflammatory activity differences between principal roots (CHW) and lateral roots (FZ) of Aconitum carmichaelii.
How strong is the evidence for Autumn Monkshood?
The strongest finding for Autumn Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Autumn Monkshood safe? What are the side effects?
No major safety issues are recorded for Autumn Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Autumn Monkshood interact with medications?
No drug interactions are recorded for Autumn Monkshood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Autumn Monkshood?
Autumn Monkshood is also known as: Борец Кармихеля, Aconit de Carmichael.
Is Autumn Monkshood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Shenfu injection in sepsis-induced acute gastrointestinal injury: a narrative review of mechanisms and current evidence. literature abstract metadata
- T2 Toxicology and detoxification processing of Fuzi (Aconitum carmichaelii Debeaux lateral root): a comprehensive review integrating historical perspectives and modern research. literature abstract metadata
- T2 Bioactive Constituents and Therapeutic Mechanisms of Shenfu Decoction in a Rat Model of Seawater-Immersion-Induced Accidental Hypothermia. literature abstract metadata
- T2 Novel insights into anti-inflammatory activity-related metabolic markers and biosynthetic regulatory mechanisms between principal and lateral roots of Aconitum carmichaelii Debx. via integrated metabolomics and transcriptomics. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata