Aconitum coreanum
Aconitum coreanum
Aconitum coreanum，一种传统植物，在亚洲医学中尤其在韩国有着深厚的历史。这种植物的具体传统用途尚未广泛记录。科学研究表明，Aconitum coreanum 可能会减少梗死面积和神经元凋亡，并通过 AMPK/mTOR/ULK1 途径抑制脑缺血性中风大鼠的自噬作用。此外，从该植物中提取的高aconitine 对 Mythimna separata 幼虫表现出显著的抗食性和毒性作用，其机制多样。已鉴定出多种二萜类化合物的生物合成，包括 tripterifordin。Aconitum coreanum 及其加工形式在仓鼠中显示出对中风的保护作用，影响 PI3K/Akt 和 KEAP1/NRF2 途径。尚未记录该植物的重大安全问题或药物相互作用；然而，由于其潜在毒性，在处理和使用时应谨慎。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- The study identifies key enzymes enabling the biosynthesis of diverse diterpenoids in Aconitum, including tripterifordin.
- 川乌及其加工形式在地鼠中通过影响PI3K/Akt和KEAP1/NRF2途径保护了其免受中风的影响。
- Aconitum coreanum 减少梗死体积和神经元凋亡，并通过AMPK/mTOR/ULK1途径抑制自噬，用于脑缺血性中风大鼠。
- 来自Aconitum coreanum的羟基甲基化aconitine在多种机制下对Mythimna separata幼虫显示出显著的毒性和拒食活性。
Frequently asked questions
What is Aconitum coreanum?
Aconitum coreanum (Aconitum coreanum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aconitum coreanum?
4 sourced findings are recorded for Aconitum coreanum; the strongest carries evidence grade D. For example: The study identifies key enzymes enabling the biosynthesis of diverse diterpenoids in Aconitum, including tripterifordin.
How strong is the evidence for Aconitum coreanum?
The strongest finding for Aconitum coreanum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aconitum coreanum safe? What are the side effects?
No major safety issues are recorded for Aconitum coreanum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aconitum coreanum interact with medications?
No drug interactions are recorded for Aconitum coreanum in our sources. This does not rule them out — check with a pharmacist.
Is Aconitum coreanum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Aconitum coreanum and processed products on its base prevent stroke via the PI3K/Akt and KEAP1/NRF2 in the in vivo study. literature abstract metadata
- T2 Divergent multifunctional P450s-empowered biosynthesis of bioactive tripterifordin and cryptic atiserenoids in Aconitum implies convergent evolution. literature abstract metadata
- T2 Toxicity of Hypaconitine from Aconitum coreanum (H. Lév.) Rapaics Against the Oriental Armyworm, Mythimna separata (Walker). literature abstract metadata
- T2 Aconitum coreanum (H.Lév l.) Rapaics exerts neuroprotective effects on cerebral ischemic stroke by inhibiting autophagy through the AMPK/mTOR/ULK1 pathway. literature abstract metadata