Aconitum coreanum
Aconitum coreanum
Aconitum coreanum，这种植物传统上在东亚医学中使用，特别是在韩国和中国。它没有广泛记录用于特定的传统用途。科学研究表明，Aconitum coreanum 在二萜类化合物如 tripterifordin 的生物合成中发挥作用，这可能对其生物学活性有所贡献。研究表明其具有潜在的神经保护作用，证据显示它可以减少脑缺血性中风模型中的梗死大小和神经元凋亡，可能是通过调节 PI3K/Akt、KEAP1/NRF2、AMPK/mTOR/ULK1 等途径。从 Aconitum coreanum 中还发现了显著的毒性以及对 Mythimna separata 幼虫的抗食性作用。这种植物没有发现重大安全问题或药物相互作用，但因其含有有毒成分而应谨慎使用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究确定了在延胡索中促进多种二萜生物合成的关键酶，包括三萜枫香脂素。
- 川乌及其加工形式在地鼠中通过影响PI3K/Akt和KEAP1/NRF2途径保护了其免受中风的影响。
- Aconitum coreanum 减少梗死体积和神经元凋亡，并通过AMPK/mTOR/ULK1途径抑制自噬，用于脑缺血性中风大鼠。
- 来自Aconitum coreanum的羟基甲基化aconitine在多种机制下对Mythimna separata幼虫显示出显著的毒性和拒食活性。
Frequently asked questions
What is Aconitum coreanum?
Aconitum coreanum (Aconitum coreanum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aconitum coreanum?
4 sourced findings are recorded for Aconitum coreanum; the strongest carries evidence grade D. For example: 研究确定了在延胡索中促进多种二萜生物合成的关键酶，包括三萜枫香脂素。
How strong is the evidence for Aconitum coreanum?
The strongest finding for Aconitum coreanum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aconitum coreanum safe? What are the side effects?
No major safety issues are recorded for Aconitum coreanum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aconitum coreanum interact with medications?
No drug interactions are recorded for Aconitum coreanum in our sources. This does not rule them out — check with a pharmacist.
Is Aconitum coreanum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Aconitum coreanum and processed products on its base prevent stroke via the PI3K/Akt and KEAP1/NRF2 in the in vivo study. literature abstract metadata
- T2 Divergent multifunctional P450s-empowered biosynthesis of bioactive tripterifordin and cryptic atiserenoids in Aconitum implies convergent evolution. literature abstract metadata
- T2 Toxicity of Hypaconitine from Aconitum coreanum (H. Lév.) Rapaics Against the Oriental Armyworm, Mythimna separata (Walker). literature abstract metadata
- T2 Aconitum coreanum (H.Lév l.) Rapaics exerts neuroprotective effects on cerebral ischemic stroke by inhibiting autophagy through the AMPK/mTOR/ULK1 pathway. literature abstract metadata