Dzungaria Monkshood
Aconitum soongaricum
Aconitum soongaricum 是一种传统药用植物，尽管其在传统实践中的具体用途尚未记录。研究表明，从这种植物中提取的加工产品可以通过调节 PI3K/AKT 信号通路来抑制卵巢癌的生长，并且显示出通过巨噬细胞极化和代谢重编程减少与骨关节炎相关的炎症的潜力。然而，这些证据仅限于实验室研究，临床试验尚未进行。Aconitine 是这种植物中发现的一种化合物，已被证明可以通过线粒体钙超载和能量代谢紊乱诱导神经元凋亡，从而显示出潜在的神经毒性作用。另一种从 Aconitum soongaricum 中分离出的二萜生物碱 Songorine 表现出抗心律失常和抗炎活性，但缺乏临床验证。迄今为止尚未发现重大安全问题或记录在案的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 加工的Aconitum soongaricum产品显著抑制了体内卵巢癌的增长，通过调节PI3K/AKT信号通路。
- 松果碱调节巨噬细胞极化和代谢重编程，减少骨关节炎中的炎症。
- aconitine通过上调MCU表达导致线粒体钙超载，从而诱导神经元凋亡，影响ATP生成和膜电位。
- 松戈林表现出多种生物学活性，包括抗心律失常、抗炎和镇静作用，但尚未进行临床测试。
Frequently asked questions
What is Dzungaria Monkshood?
Dzungaria Monkshood (Aconitum soongaricum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dzungaria Monkshood?
4 sourced findings are recorded for Dzungaria Monkshood; the strongest carries evidence grade D. For example: 加工的Aconitum soongaricum产品显著抑制了体内卵巢癌的增长，通过调节PI3K/AKT信号通路。
How strong is the evidence for Dzungaria Monkshood?
The strongest finding for Dzungaria Monkshood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dzungaria Monkshood safe? What are the side effects?
No major safety issues are recorded for Dzungaria Monkshood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dzungaria Monkshood interact with medications?
No drug interactions are recorded for Dzungaria Monkshood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dzungaria Monkshood?
Dzungaria Monkshood is also known as: Борец джунгарский.
Is Dzungaria Monkshood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Therapeutic potential of songorine, a diterpenoid alkaloid of the genus Aconitum. literature abstract metadata
- T2 Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU. literature abstract metadata
- T2 Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis. literature abstract metadata
- T2 Processed Products of Aconitum soongaricum Stapf. Inhibit the Growth of Ovarian Cancer Cells In vivo via Regulating the PI3K/AKT Signal Pathway. literature abstract metadata