White sapote
Casimiroa edulis
Casimiroa edulis, commonly known as ice-apple or white sapote, is a tree native to Central America and Mexico. While it has been used in traditional practices for various purposes such as food and folk remedies, no specific traditional uses have been recorded. Scientific studies indicate that Casimiroa edulis may improve sperm quality and restore testicular enzyme activity in diabetic male rats, suggesting potential benefits in male reproductive health. Additionally, extracts from its leaves show vasorelaxation effects through nitric oxide release and calcium channel blockade, as well as suppression of MMP9 expression via the JAK/STAT3 pathway and TNFα-dependent pathways. A leaf extract encapsulated in biodegradable nanoparticles demonstrated antioxidant activity, though further efficacy studies are required to confirm these findings. No major safety issues or drug interactions have been reported for Casimiroa edulis.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Casimiroa edulis treatment improved sperm quality and restored testicular enzyme activity in diabetic male rats.
- 用己烷和二氯甲烷从卡斯米罗亚·埃杜里斯树叶中提取的物质通过释放NO和阻断钙通道在大鼠身上诱导了血管舒张。
- 卡西多隆（来自卡西莫罗埃杜利斯）通过抑制JAK/STAT3途径和TNFα依赖途径来抑制MMP9的表达。
- 从Casimiroa edulis叶片提取物被封装在生物可降解纳米颗粒中显示出抗氧化活性，但需要进一步的疗效研究。
Frequently asked questions
What is White sapote?
White sapote (Casimiroa edulis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about White sapote?
4 sourced findings are recorded for White sapote; the strongest carries evidence grade D. For example: Casimiroa edulis treatment improved sperm quality and restored testicular enzyme activity in diabetic male rats.
How strong is the evidence for White sapote?
The strongest finding for White sapote carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is White sapote safe? What are the side effects?
No major safety issues are recorded for White sapote in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does White sapote interact with medications?
No drug interactions are recorded for White sapote in our sources. This does not rule them out — check with a pharmacist.
What are the common names of White sapote?
White sapote is also known as: Белая сапота, Sapote blanche.
Is White sapote a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Methoxylated Flavones from Casimiroa edulis La Llave Suppress MMP9 Expression via Inhibition of the JAK/STAT3 Pathway and TNFα-Dependent Pathways. literature abstract metadata
- T2 Vasorelaxant and Antihypertensive Effects of Extracts from the Leaves of Casimiroa edulis La Llave (Rutaceae) by NO Release and Calcium Channel Blockade. literature abstract metadata
- T2 Casimiroa edulis extract modulates testosterone levels, testicular enzymes and spermatogenesis disorders in streptozotocin-induced diabetic male rats. literature abstract metadata
- T2 Casimiroa edulis Leaf Extract-Loaded PLGA Nanoparticles: Untargeted Phytochemical Profiling and Wound-Healing-Oriented Antioxidant/Occlusive Characterization. literature abstract metadata