Sapote blanche
Casimiroa edulis · White sapote
Casimiroa edulis, commonly known as ice-apple or white sapote, is a tree native to Central America and Mexico. While it has been used in traditional practices for various purposes such as food and folk remedies, no specific traditional uses have been recorded. Scientific studies indicate that Casimiroa edulis may improve sperm quality and restore testicular enzyme activity in diabetic male rats, suggesting potential benefits in male reproductive health. Additionally, extracts from its leaves show vasorelaxation effects through nitric oxide release and calcium channel blockade, as well as suppression of MMP9 expression via the JAK/STAT3 pathway and TNFα-dependent pathways. A leaf extract encapsulated in biodegradable nanoparticles demonstrated antioxidant activity, though further efficacy studies are required to confirm these findings. No major safety issues or drug interactions have been reported for Casimiroa edulis.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Casimiroa edulis treatment improved sperm quality and restored testicular enzyme activity in diabetic male rats.
- Les extraits obtenus par hexane et dichlorométhane des feuilles de Casimiroa edulis ont provoqué une relaxation vasculaire par libération de NO et blocage des canaux de calcium chez les rats.
- Les casédulones de Casimiroa edulis réduisent l'expression de MMP9 par l'inhibition du chemin JAK/STAT3 et des chemins dépendants de TNFα.
- Un extrait de feuille de Casimiroa edulis a été encapsulé dans des nanoparticules biodégradables montrant une activité antioxydante, mais des études d'efficacité sont nécessaires.
Frequently asked questions
What is Sapote blanche?
Sapote blanche (Casimiroa edulis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Sapote blanche?
4 sourced findings are recorded for Sapote blanche; the strongest carries evidence grade D. For example: Casimiroa edulis treatment improved sperm quality and restored testicular enzyme activity in diabetic male rats.
How strong is the evidence for Sapote blanche?
The strongest finding for Sapote blanche carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Sapote blanche safe? What are the side effects?
No major safety issues are recorded for Sapote blanche in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Sapote blanche interact with medications?
No drug interactions are recorded for Sapote blanche in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Sapote blanche?
Sapote blanche is also known as: White sapote, Белая сапота.
Is Sapote blanche a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Methoxylated Flavones from Casimiroa edulis La Llave Suppress MMP9 Expression via Inhibition of the JAK/STAT3 Pathway and TNFα-Dependent Pathways. literature abstract metadata
- T2 Vasorelaxant and Antihypertensive Effects of Extracts from the Leaves of Casimiroa edulis La Llave (Rutaceae) by NO Release and Calcium Channel Blockade. literature abstract metadata
- T2 Casimiroa edulis extract modulates testosterone levels, testicular enzymes and spermatogenesis disorders in streptozotocin-induced diabetic male rats. literature abstract metadata
- T2 Casimiroa edulis Leaf Extract-Loaded PLGA Nanoparticles: Untargeted Phytochemical Profiling and Wound-Healing-Oriented Antioxidant/Occlusive Characterization. literature abstract metadata