Adlay
Coix lacryma-jobi
Coix lacryma-jobi，通常被称为伊博泪或科克斯种子，是一种传统植物，在东亚医学中被使用。其传统的用途没有很好地记录；然而，它被用于各种目的，如食物和酿酒。科学证据表明，当与托里帕利马布和其他治疗方法（如化疗）结合时，Coix lacryma-jobi可能在癌症治疗中有潜力，显示出可管理的安全性和初步的抗肿瘤活性，在晚期非小细胞肺癌患者中尤为明显，尽管还需要进一步验证。此外，科克斯种子还通过涉及HIF-1α激活和NF-κB抑制的机制表现出对骨骼健康的功效，通过抑制成骨细胞分化和吸收。另外，Coix lacryma-jobi还被用于通过TRV-VIGS系统研究宿主病原体相互作用，突显了其在增加易感性和增强抵抗力方面的用途。从安全性来看，没有记录到重大问题，并且目前没有报告与该植物相关的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 康莱特注射液与托里帕利单抗和化疗联合使用在晚期NSCLC患者中显示出了可管理的安全性和初步的抗肿瘤活性，但这些发现仍需验证。
- 科希老抑制了体内外的成骨细胞分化和骨吸收，通过激活HIF-1α并抑制NF-κB信号传导。
- 该研究建立了一个TRV-VIGS系统来研究高粱中的宿主-病原体相互作用，并通过甲基乙二醛提高了基因沉默效率。
- Coix lacryma-jobi 种子在铵盐/硝酸盐比例为50/50时表现出最佳的碳积累，极端比例下效率降低。
- The study found that coix seed powder increased terpenoid and flavonoid accumulation in Taiwanofungus gaoligongensis, particularly sesquiterpenoids and isoflavones.
Frequently asked questions
What is Adlay?
Adlay (Coix lacryma-jobi) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Adlay?
5 sourced findings are recorded for Adlay; the strongest carries evidence grade D. For example: 康莱特注射液与托里帕利单抗和化疗联合使用在晚期NSCLC患者中显示出了可管理的安全性和初步的抗肿瘤活性，但这些发现仍需验证。
How strong is the evidence for Adlay?
The strongest finding for Adlay carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Adlay safe? What are the side effects?
No major safety issues are recorded for Adlay in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Adlay interact with medications?
No drug interactions are recorded for Adlay in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Adlay?
Adlay is also known as: Иовлевы слёзы, Coix larme-de-Job, Larme-de-Job, Herbe à chapelets.
Is Adlay a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Coixol attenuates osteoclastogenesis and ovariectomy-induced bone loss via the HIF-1α-mediated suppression of NF-κB signaling. literature abstract metadata
- T2 Multi-omics analysis Taiwanofungus gaoligongensis fermentation with traditional Chinese medicine. literature abstract metadata
- T2 Elucidation of inorganic nitrogen utilization characteristics in Coix lacryma-jobi L. seedlings under variable ammonium/nitrate ratios via the 15N tracer technique. literature abstract metadata
- T2 Establishment of a TRV-VIGS system in Coix (Coix lacryma-jobi L.) for functional study of host-pathogen interactions. literature abstract metadata
- T2 Safety and Clinical Outcomes of Kanglaite Injection in Combination with Toripalimab and Chemotherapy for Advanced Non-Small Cell Lung Cancer: A Real-World Retrospective Analysis. literature abstract metadata