Adlay
Coix lacryma-jobi
Coix lacryma-jobi is a plant utilized within various traditional medicinal practices. It is traditionally applied to address conditions such as rheumatism, diarrhea, headaches, bladder complaints, and various inflammatory or blood disorders. Scientific evidence regarding its therapeutic properties is limited and varies in strength. Some preliminary studies suggest that a combination involving Kanglaite injection may show manageable safety and potential antitumor activity in advanced NSCLC, though these findings require further validation. Additionally, coixol has demonstrated the ability to inhibit osteoclast differentiation in laboratory settings. No major safety issues or notable drug interactions have been recorded.
- Traditionally for
- diuretic · rheumatism
- Traditions
- Unani · TCM · traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- diuretic
- rheumatism
- diarrhea
- headache
- pectoral
- urogenital complaints
- abscess
- anodyne
- anthrax
- appendicitis
- arthritis
- beriberi
- bladder complaints
- blood disorders
- bronchitis
What the science says
- The combination of Kanglaite injection with toripalimab and chemotherapy showed manageable safety and preliminary antitumor activity in advanced NSCLC patients, though findings need validation.
- Coixol inhibited osteoclast differentiation and bone resorption both in vitro and in vivo by activating HIF-1α and suppressing NF-κB signaling.
- The study established a TRV-VIGS system for Coix to study host-pathogen interactions, enhancing gene silencing efficiency with methylglyoxal.
- Coix lacryma-jobi seedlings showed optimal carbon accumulation under a 50/50 ammonium/nitrate ratio, with reduced efficiency at extreme ratios.
- The study found that coix seed powder increased terpenoid and flavonoid accumulation in Taiwanofungus gaoligongensis, particularly sesquiterpenoids and isoflavones.
Frequently asked questions
What is Adlay?
Adlay (Coix lacryma-jobi) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Adlay traditionally used for?
Traditional sources record Adlay for: diuretic, rheumatism, diarrhea, headache, pectoral, urogenital complaints. This reflects traditional use, not a proven medical treatment.
Which traditions use Adlay?
Adlay appears in these traditions in our sources: Unani, TCM, traditional.
What does the scientific evidence say about Adlay?
5 sourced findings are recorded for Adlay; the strongest carries evidence grade D. For example: The combination of Kanglaite injection with toripalimab and chemotherapy showed manageable safety and preliminary antitumor activity in advanced NSCLC patients, though findings need validation.
How strong is the evidence for Adlay?
The strongest finding for Adlay carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Adlay safe? What are the side effects?
No major safety issues are recorded for Adlay in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Adlay interact with medications?
No drug interactions are recorded for Adlay in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Adlay?
Adlay is also known as: Иовлевы слёзы, Coix larme-de-Job, Larme-de-Job, Herbe à chapelets.
Is Adlay a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Coixol attenuates osteoclastogenesis and ovariectomy-induced bone loss via the HIF-1α-mediated suppression of NF-κB signaling. literature abstract metadata
- T2 Multi-omics analysis Taiwanofungus gaoligongensis fermentation with traditional Chinese medicine. literature abstract metadata
- T2 Elucidation of inorganic nitrogen utilization characteristics in Coix lacryma-jobi L. seedlings under variable ammonium/nitrate ratios via the 15N tracer technique. literature abstract metadata
- T2 Establishment of a TRV-VIGS system in Coix (Coix lacryma-jobi L.) for functional study of host-pathogen interactions. literature abstract metadata
- T2 Safety and Clinical Outcomes of Kanglaite Injection in Combination with Toripalimab and Chemotherapy for Advanced Non-Small Cell Lung Cancer: A Real-World Retrospective Analysis. literature abstract metadata