Small corydalis
Corydalis ambigua
Corydalis ambigua 是一种传统上在某些亚洲医学实践中使用的植物，特别是在中国。它因其潜在的抗癌作用而闻名，因为研究表明 Corydalis ambigua 可以通过调节 c-Myc 表达诱导结肠癌细胞凋亡和细胞周期停滞。此外，研究还表明该植物的开花时间因雪融化时间的不同而在不同种群中有所变化，这可能会影响种子产量并潜在地破坏与传粉者的生态学同步性。植物中的活性成分 acetylcorynoline 通过 UPLC-MS/MS 方法研究了其药代动力学和生物利用度。l-threo-hypaconitine (l-THP) 在细胞培养中也显示出潜力，因为它可以抑制 α4β2 尼古丁受体对尼古丁的反应。尽管 Corydalis ambigua 没有记录到重大安全问题或已知药物相互作用，但进一步的研究对于全面了解其更广泛的用途和效果仍然是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自 Corydalis ambigua 的 ACN 在结肠癌细胞中诱导凋亡和细胞周期停滞，通过调节 c-Myc 表达。
- 紫堇 Corydalis ambigua 的开花时间因不同融雪时间的种群而异，这可能会影响种子产量，因为其花期与传粉者可能存在潜在的物候不匹配。
- 该研究开发并验证了UPLC-MS/MS方法以确定小鼠血浆中乙酰柯罗宁的含量，展示了其药代动力学和生物利用度。
- l-THP 抑制SH-EP1 细胞中α4β2型尼古丁受体对尼古丁的反应。
Frequently asked questions
What is Small corydalis?
Small corydalis (Corydalis ambigua) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Small corydalis?
4 sourced findings are recorded for Small corydalis; the strongest carries evidence grade D. For example: 来自 Corydalis ambigua 的 ACN 在结肠癌细胞中诱导凋亡和细胞周期停滞，通过调节 c-Myc 表达。
How strong is the evidence for Small corydalis?
The strongest finding for Small corydalis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Small corydalis safe? What are the side effects?
No major safety issues are recorded for Small corydalis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Small corydalis interact with medications?
No drug interactions are recorded for Small corydalis in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Small corydalis?
Small corydalis is also known as: Хохлатка обманчивая.
Is Small corydalis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. literature abstract metadata
- T2 Acetylcorynoline Induces Apoptosis and G2/M Phase Arrest through the c-Myc Signaling Pathway in Colon Cancer Cells. literature abstract metadata
- T2 Determination and Pharmacokinetics of Acetylcorynoline in Mouse Plasma by UPLC-MS/MS. literature abstract metadata
- T2 Site-specific variation in flowering phenology of a spring ephemeral plant and its implications for phenological mismatch with pollinators under climate change. literature abstract metadata