Bunge’s corydalis
Corydalis bungeana
Corydalis bungeana，一种传统草药植物，在东亚传统草药实践中主要被使用。尽管其具体的传统用途尚不明确，但初步科学研究表明它在各种疾病中具有潜在的治疗效果。研究表明，与之密切相关的 Corydalis yanhusuo 植物化合物可能通过抑制TLR4/JNK/NF-κB途径减少肝损伤，并且已经证明它们可以通过Src/JNK信号通路介导的G2/M期阻滞和线粒体凋亡在成骨肉瘤细胞中表现出抗肿瘤特性。此外，有证据表明 Corydalis bungeana 化合物可能与雌激素受体1（ESR1）和SRC蛋白相互作用，以潜在地治疗多囊卵巢综合征（PCOS）。此外，存在于 Corydalis bungeana 中的科瑞诺林通过调节STAT3/Bcl-2信号通路抑制胶质母细胞瘤细胞增殖。目前尚未发现 Corydalis bungeana 的主要安全问题或记录到的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- AC通过在体内外实验中抑制TLR4/JNK/NF-κB途径来减少肝损伤。
- Corynoline 抑制成骨肉瘤细胞的增殖并促进通过Src/JNK信号通路介导的G2/M期阻滞和线粒体凋亡而诱导凋亡。
- 研究发现， Corydalis bungeana 成分通过与 ESR1 和 SRC 蛋白质的相互作用，在PCOS 中具有潜在的治疗效果。
- Corynoline 抑制了胶质母细胞瘤细胞的增殖并促进了通过调节STAT3/Bcl-2信号通路的凋亡。
Frequently asked questions
What is Bunge’s corydalis?
Bunge’s corydalis (Corydalis bungeana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bunge’s corydalis?
4 sourced findings are recorded for Bunge’s corydalis; the strongest carries evidence grade D. For example: AC通过在体内外实验中抑制TLR4/JNK/NF-κB途径来减少肝损伤。
How strong is the evidence for Bunge’s corydalis?
The strongest finding for Bunge’s corydalis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bunge’s corydalis safe? What are the side effects?
No major safety issues are recorded for Bunge’s corydalis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bunge’s corydalis interact with medications?
No drug interactions are recorded for Bunge’s corydalis in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bunge’s corydalis?
Bunge’s corydalis is also known as: Хохлатка Бунге.
Is Bunge’s corydalis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Acetylcorynoline alleviates acute liver injury via inhibiting TLR4/JNK/NF-ĸB pathway Based on RNA-seq and molecular docking in vivo and in vitro. literature abstract metadata
- T2 Anti-osteosarcoma activity of Corynoline via Src/JNK signaling-mediated cell cycle arrest and mitochondrial apoptosis. literature abstract metadata
- T2 Corynoline promotes apoptosis and inhibits proliferation of glioblastoma via regulating the STAT3/Bcl-2 signalling pathway. literature abstract metadata
- T2 Therapeutic potential of Corydalis alkaloids in polycystic ovary syndrome: In silico and preliminary In vitro Insights into ESR1 and SRC-associated pathways. literature abstract metadata