Bunge’s corydalis
Corydalis bungeana
Corydalis bungeana，一种传统草药植物，在东亚草药实践中主要被使用。尽管其具体用途尚未详细记录，但研究表明它在多种研究中显示出潜在的治疗效果。科学证据表明，科迪利莎·bungéna化合物可能通过与雌激素受体和SRC途径相互作用对多囊卵巢综合征（PCOS）有益。此外，AC（可能是植物中的化合物）可以通过抑制TLR4/JNK/NF-κB途径减少肝损伤。其他研究表明，另一种化合物corynoline可以抑制胶质母细胞瘤细胞增殖并促进凋亡通过STAT3/Bcl-2信号通路，并且还可以通过Src/JNK信号通路介导的G2/M期停滞和线粒体凋亡抑制成骨肉瘤细胞增殖。目前的安全问题很小，没有记录到主要的问题，也没有报告有关药物相互作用的证据。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- AC通过在体内外实验中抑制TLR4/JNK/NF-κB途径来减少肝损伤。
- Corynoline 抑制成骨肉瘤细胞的增殖并促进通过Src/JNK信号通路介导的G2/M期阻滞和线粒体凋亡而诱导凋亡。
- 研究发现， Corydalis bungeana 成分通过与 ESR1 和 SRC 蛋白质的相互作用，在PCOS 中具有潜在的治疗效果。
- Corynoline 抑制了胶质母细胞瘤细胞的增殖并促进了通过调节STAT3/Bcl-2信号通路的凋亡。
Frequently asked questions
What is Bunge’s corydalis?
Bunge’s corydalis (Corydalis bungeana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bunge’s corydalis?
4 sourced findings are recorded for Bunge’s corydalis; the strongest carries evidence grade D. For example: AC通过在体内外实验中抑制TLR4/JNK/NF-κB途径来减少肝损伤。
How strong is the evidence for Bunge’s corydalis?
The strongest finding for Bunge’s corydalis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bunge’s corydalis safe? What are the side effects?
No major safety issues are recorded for Bunge’s corydalis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bunge’s corydalis interact with medications?
No drug interactions are recorded for Bunge’s corydalis in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bunge’s corydalis?
Bunge’s corydalis is also known as: Хохлатка Бунге.
Is Bunge’s corydalis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Acetylcorynoline alleviates acute liver injury via inhibiting TLR4/JNK/NF-ĸB pathway Based on RNA-seq and molecular docking in vivo and in vitro. literature abstract metadata
- T2 Anti-osteosarcoma activity of Corynoline via Src/JNK signaling-mediated cell cycle arrest and mitochondrial apoptosis. literature abstract metadata
- T2 Corynoline promotes apoptosis and inhibits proliferation of glioblastoma via regulating the STAT3/Bcl-2 signalling pathway. literature abstract metadata
- T2 Therapeutic potential of Corydalis alkaloids in polycystic ovary syndrome: In silico and preliminary In vitro Insights into ESR1 and SRC-associated pathways. literature abstract metadata