FolkKB

Cryptolepis dubia

Cryptolepis dubia

Cryptolepis dubia 是一种传统上未用于任何已知医疗实践的植物。科学研究已经从这种植物中鉴定出几种甾体化合物，(-)-cryptanoside A 展现出强大的细胞毒性及 NKA 抑制活性，表明其可能具有抗肿瘤作用。两种分离出来的 leuconoxine 类型的二氮杂螺吲哚生物碱也显示出对人类卵巢癌细胞的选择性细胞毒性。Cryptolepis buchananii 果实中发现了四种新的五环三萜糖苷，并且这些化合物显著抑制了 NO 的产生，表明可能具有抗炎作用。虽然尚未记录到主要的安全问题或药物相互作用，但目前的证据有限，需要更多的研究来全面了解其潜在的治疗应用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • Cryptolepis dubia 产生了几种甾体化合物，(-)-cryptanoside A 展现出很强的细胞毒性和NKA 抑制活性。 D PMID
  • 从Cryptolepis dubia中分离出两种leuconoxine型二氮杂螺旋吲哚生物碱，并显示对人类卵巢癌细胞OVCAR3的选择性细胞毒性。 D PMID
  • 从Cryptolepis buchananii果实中分离出四种新的五环三萜苷，并且在LPS激活的RAW264.7细胞中显示出显著抑制NO产生。 D PMID
  • (-)-Cryptanoside A 来自 Cryptolepis dubia，对多种人类癌细胞系显示出强烈的细胞毒性，并且具有对癌细胞的选择性。 D PMID

Frequently asked questions

What is Cryptolepis dubia?

Cryptolepis dubia (Cryptolepis dubia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Cryptolepis dubia?

4 sourced findings are recorded for Cryptolepis dubia; the strongest carries evidence grade D. For example: Cryptolepis dubia 产生了几种甾体化合物，(-)-cryptanoside A 展现出很强的细胞毒性和NKA 抑制活性。

How strong is the evidence for Cryptolepis dubia?

The strongest finding for Cryptolepis dubia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Cryptolepis dubia safe? What are the side effects?

No major safety issues are recorded for Cryptolepis dubia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Cryptolepis dubia interact with medications?

No drug interactions are recorded for Cryptolepis dubia in our sources. This does not rule them out — check with a pharmacist.

Is Cryptolepis dubia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets. literature abstract metadata
  2. T2 Four New Pentacyclic Triterpene Glycosides Isolated from the Fruits of Cryptolepis buchananii R.Br. ex Roem. & Schult and Their Inhibition of NO Production in LPS-activated RAW264.7 Cells. literature abstract metadata
  3. T2 Cytotoxic leuconoxine-type diazaspiroindole alkaloids isolated from Cryptolepis dubia. literature abstract metadata
  4. T2 Cytotoxic and Noncytotoxic Steroidal Constituents of Cryptolepis dubia. literature abstract metadata